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1st Edition

Microbiological Quality Assurance A Guide Towards Relevance and Reproducibility of Inocula

By M.R.W. Brown Copyright 1995
    ISBN 9781315895451
    317 Pages
    Published November 29, 2017 by CRC Press

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    Microbiological Quality Assurance: A Guide Towards Relevance and Reproducibility of Inocula sheds light on the difficulties of obtaining results in the test tube that will be reproducible and relevant for a wide variety of tests. This book explores the current state of research in this area and troubleshoots the problems that may be encountered in setting up appropriate cultures. The text divides naturally into three sections-growth conditions, post-growth conditions, and applications. This book serves as a valuable resource for clinical microbiologists, pharmacologists, and anyone doing in vitro experiments.

    1. Influence of the Environment on the Properties of Vegetative Microorganisms: An Overview 2. Definition of Phenotype in Batch Culture 3. Changes in Bacterial Cell Properties in Going from Exponential Growth to Stationary Phase 4. Continuous Culture of Microorganisms in Liquid Media: Effects of Growth Rate and Nutrient Limitation 5. The Influence of Nutrient Environment during Vegetative Growth on the Properties of Bacterial Endospores 6. Influence of the Environment on the Properties of Microorganisms Grown in Association with Surfaces 7. Sources of Biological Variation and Lack of Inoculum Reproducibility: A Summary 8. The Preservation of Inocula 9. Influence of Post-Growth Procedures on the Properties of Microorganisms 10. Factors Affecting the Reproducibility and Predictivity of Performance Tests, P 11. Preservative Efficacy Testing in the Pharmaceuticals and Cosmetics Industries 12. Preservative Efficacy Testing in the Cosmetics and Toiletries Industries 13. Reproducibility and Predictivity of Disinfection and Biocide Tests 14. Reproducibility and Performance of Endospores as Biological Indicators 15. Development and Production of Vaccines 16. Screening for Novel Antimicrobial Activity/Compounds in the Pharmaceutical Industry 17. Screening for Novel Antimicrobial Compounds/Activity in the Environmental Protection Industries 18. Antimicrobial Susceptibility Testing within the Clinic

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