Microcompartmentation: 1st Edition (Hardback) book cover

Microcompartmentation

1st Edition

By D.P. Jones

CRC Press

273 pages

Purchasing Options:$ = USD
Hardback: 9781315895475
pub: 2017-11-29
SAVE ~$41.00
$205.00
$164.00
x
eBook (VitalSource) : 9781351074575
pub: 2018-01-18
from $28.98


FREE Standard Shipping!

Description

Microcompartmentation refers to nonhomogeneous distribution of solutes in compartments of cells or associated structures without intervening membranal barriers. Such variations in concentration of ions, metabolites, intracellular messengers, and nutrients can introduce significant heterogeneity in subcellular function and regulation. The current focus on biological examples of microcompartmentation provides ample evidence for its importance and the role of physical structure in determining local chemical environments. The examples present in the different chapters include microcompartmentation of Ca2+,H+,ATP. ADP, O2, glycolytic intermediates, fatty acids, amino acids, and nucleic acid precursors. In reviewing these systems, the authors provide a useful resource for experimental approaches to study microcompartmentation and provide the basis for future studies of its role in regulation of cell functions.

Table of Contents

1. On the Internal Environment of Animal Cells 2. Functional Compartmentation of Carbohydrate Metabolism 3. Mitochondrial Distribution and 02 Gradients in Mammalian Cells 4. Involvement of Microcompartmentation in the Regulation of Cell Proliferation 5. Diffusion and Ultrastructural Adaptive Responses in Ectotherms 6. Microcompartmentation of Metabolite Transport in Mitochondria 7. The Membranes Involved in Proton-Mediated Free-Energy Transduction: Thermodynamic Implications of their Physical Structure 8. Microcompartmentation of DNA Precursors 9. Function of Ambiquitous Proteins in a Heterogeneous Medium 10. Microzonation of ATP and pH in the Aqueous Cytoplasm of Mammalian Cells 11. Hyrdrogen and Calcium Ion Diffusion in Axoplasm 12. Fluorescence Digital Imaging Microscopy � Spatial Distribution of Ca2+ and H+ in single Cells

Subject Categories

BISAC Subject Codes/Headings:
SCI017000
SCIENCE / Life Sciences / Cytology
SCI086000
SCIENCE / Life Sciences / General