Microfluidics and Nanotechnology Biosensing to the Single Molecule Limit

Preface

Editors

Contributors

Toward Unsupervised Smart Chemical Sensor Arrays
Leonardo Tomazeli Duarte and Christian Jutten

Active CMOS Biochip for Electrochemical DNA Assays
Peter M. Levine, Ping Gong, Rastislav Levicky, and Kenneth L. Shepard

Label-Free DNA Sensor Based on a Surface Long-Period Grating
Young-Geun Han

Measuring the Physical Properties of Cells
Shirin Mesbah Oskui and William H. Grover

Technologies for Low-Cost, Hall Effect-Based Magnetic Immunosensors
Simone Gambini

Two-Dimensional Paper Networks for Automated Multistep Processes in Point-of-Care Diagnostics
Elain Fu, Barry Lutz, and Paul Yager

Droplet-Based Digital Microfluidics for Single-Cell Genetic Analysis
Yong Zeng and Richard A. Mathies

Droplet-Based Microfluidics for Biological Sample Preparation and Analysis
Xuefei Sun and Ryan T. Kelly

A Review of Tubeless Microfluidic Devices
Pedro J. Resto, David J. Beebe, and Justin C. Williams

Index

Biography

Dr. Eric T. Lagally holds a Ph.D from the University of California (UC)-Berkeley/UC-San Francisco Graduate Program in Bioengineering, USA. Currently, he is a faculty member at Western Governors University, Salt Lake City, Utah, USA. Previously, he founded and consulted for Lagally Consulting, and served as assistant professor at the University of British Columbia, Vancouver, Canada, where his research program was responsible for developing multiplexed surface plasmon resonance microfluidics as well as dielectrophoresis chips for whole-cell detection of Mycobacterium tuberculosis. A co-inventor on patents for microfluidic valve technologies and aptamer selection techniques, he has published numerous peer-reviewed, conference-proceeding, and review papers and chapters in edited books.

Dr. Krzysztof (Kris) Iniewski is managing R&D at Redlen Technologies Inc., Vancouver, British Columbia, Canada, a leading manufacturer of high resolution cadmium zinc telluride semiconductor radiation detectors. He is also president of CMOS Emerging Technologies Research Inc., Coquitlam, British Columbia, Canada, an organization hosting high-tech events on communications, microsystems, optoelectronics, and sensors. A popular speaker and consultant, he has published over 100 research papers, written and edited several books, and held faculty and management positions at University of Toronto, Ontario, Canada; University of Alberta, Edmonton, Canada; Simon Fraser University, Burnaby, British Columbia, Canada; and PMC-Sierra Inc., Burnaby, British Columbia, Canada.

The book Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit, edited by Eric Lagally, offers a unique collection of detection technologies and fluidic strategies that provides inspiration for improved integration of such fields. This text provides a timely comparison of complementary advancements in biosensors and microfluidics, with state-ofthe- art developments reviewed by renowned experts.
This book represents an important contribution to the fields of microfluidics, biosensing, and single-cell analysis. The level of detail is appropriate for scientists and PhD students interested in using microfluidics for biosensing or cellular applications—perhaps in the format of a special-topics graduate course. Due to its unique yet complementary arrangement, the text provides an important perspective to all readers, but particularly for those interested in developing a new program. In this way, this book can serve as an inspiration piece for more junior scientists thinking of starting their own research group.
With its creative combination of complementary detection and fluidic technologies, this book should prove to be a timely resource for scientists looking to make an impact in biological research using novel tools such as those described within its pages.
—Springer-Verlag GmbH Germany, part of Springer Nature 2018