1st Edition

Microneedling in Clinical Practice

Edited By Boris Stoeber, Raja K. Sivamani, Howard Maibach Copyright 2021
    158 Pages 36 Color & 6 B/W Illustrations
    by CRC Press

    158 Pages 36 Color & 6 B/W Illustrations
    by CRC Press

    158 Pages 36 Color & 6 B/W Illustrations
    by CRC Press

    Microneedles provide an artificial pathway across the skin barrier for medical and cosmetic applications. This technology has seen a significant increase in popularity over the past years; as an example, the use of multiple small needles mounted on a roller to pierce the skin, prompting it to stimulate collagen production, has undergone a resurgence of interest as an adjunctive procedure for a number of skin disorders. This monograph draws together what is known about how to integrate microneedle technology into clinical dermatologic practice.

    List of Contributors

    1. Microneedles and Trandermal Transport
    2. Ashley Clarke and Raja Sivamani

    3. Skin perforation and solid microneedles
    4. Michael L Crichton and Mark Kendall

    5. Dissolvable and Coated Microneedle Arrays: Design, Fabrication, Materials, and Administration Methods
    6. Emrullah Korkmaz and O. Burak Ozdoganlar

    7. Hollow Microneedles
    8. Iman Mansoor and Boris Stoeber

    9. Microneedles vs other transdermal technologies
    10. Yeakuty Jhanker, James H.N. Tran, Tarl W. Prow, and Heather A.E. Benson

    11. Combination of Microneedles with other methods
    12. Sahitya Katikaneni

    13. Medical Applications of Microneedles
    14. Samantha Tran and Raja Sivamani

    15. Therapeutic drug and biomolecule monitoring potential for microneedle technologies
    16. Sahan A. Ranamukhaarachchi and Urs O. Häfeli

    17. Commercialized Microneedles
    18. Kang Ju Lee, Seung Hyun Park, Ji Yong Lee, and Won Hyoung Ryu

    19. Considerations for Clinical Trials Involving Microneedle Devices
    20. Janet Tamada

    21. Cosmetic Applications
    22. Aunna Pourang and Kourosh Beroukhim

    23. Dermatotoxicology of Microneedles in Man

    John Havens Cary, Becky S. Li, and Howard I. Maibach



    Boris Stoeber, PEng, PhD is Professor, Mechanical Engineering and Electrical and Computer Engineering, Research Chair in Microfluidics and Sensing Technology, Faculty of Applied Science, University of British Columbia, Vancouver

    Raja K Sivamani, MD, MS (Bioengineering), AP is  Ayurvedic Practitioner, Pacific Skin Institute; Adjunct Associate Professor of Clinical Dermatology, Director of Clinical Research, University of California, Davis; Associate Professor of Dermatology, California Northstate University, College of Medicine; and Adjunct Assistant Professor, Co-Director of Microbiome Labs Research Initiative, Department of Biological Sciences, California State University, Sacramento

    Howard I. Maibach, MD is Professor, Dermatology, School of Medicine, University of California at San Francisco