FOREWORD. INTRODUCTION. Historical Background (F.D.K. Liddell). MINERAL FIBERS: OCCURRENCE, PRODUCTION, PROPERTIES, USES. Occurrence, Production, Properties and Uses of Asbestiform Fibers (R.E.G. Rendall). Occurrence, Production, Properties and Uses of Naturally Occurring Fibers Other Than Asbestos (G.W. Gibbs). Production, Applications and Manufacture of Man-Made Mineral Fibers (J. Young). FIBERS AS POTENTIAL HEALTH HAZARDS. Airborne Dusts (W.H. Walton). Asbestos in the Occupational Environment (F.D.K. Liddell). Environmental Measurements of Man-Made Fibers (M.E. Meek). Fibers in the General Environment (A.P. Rood). EPIDEMIOLOGY OF FIBER-RELATED DISEASES. The Epidemiology of Asbestosis (M.R. Becklake). Pleural and Airway Disease Associated with Mineral Fibers (P.E. Ernst and J. Zedja). Epidemiology of Lung Cancer in Relation to Asbestos Exposure (J. Hughes). Epidemiology of Mesothelioma (J.C. and A.D. McDonald). Lung Cancer and Mesothelioma Related to Other Natural Mineral Fibers (L. Simonato). Lung Cancer and Mesothelioma Related to MMMF: The Epidemiologic Evidence (M.E. Meek). Other Aspects of Asbestos-Related Malignancies (F.D.K. Liddell). Inconsistencies and Limitations (J. Bignon). PATHOGENESIS AND MODES OF ACTION. Physico-Chemical Properties of Asbestos as Determinants of Biological Potential (A. Langer, R. Nolan, and J. Addison). Pulmonary Deposition and Clearance of Airborne Mineral Fibers (P. Sébastien). Information Obtained from Fiber-Induced Lesions in Animals (J.M.G. Davis). Lung Cancer and Mesothelioma Related to Man-Made Mineral Fibers: The Toxicological Evidence (M.E. Meek). Pulmonary Immunobiological Effects Related to the Inhalation of Mineral Fibers (D.S. Warheit and K. Miller). Mechanisms of Action of Mineral Fibers Studied by In Vitro Methods (J.M. Petruska, R.C. Brown, B. Mossman, and J.A. Hoskins). CONFLICTS. Conflicts in the Evidence on the Health Effects of Mineral Fibers (P. Elmes). MINERAL FIBERS AND FUTURE HEALTH. The Need for Mineral Fibers (J. Dunnigan). Alternatives to Mineral Fibers (U.F. Gruber). Mineral Fibers in the Nonoccupational Environment (R. Doll). Summing Up (F.D.K. Liddell and Klara Miller).