Monoclonal Antibodies: Cytokines and Arthritis, Mediators of Inflammation and Therapy, 1st Edition (Paperback) book cover

Monoclonal Antibodies

Cytokines and Arthritis, Mediators of Inflammation and Therapy, 1st Edition

By Kresina

CRC Press

512 pages

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Description

Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of

Table of Contents

1. Monoclonal Antibodies: New Horizons in the Treatment of Human Autoimmune Disease. 2. Therapeutic Application of Monoclonal Antibodies in the Rheumatic Diseases 3. Treatment of Patients with Rheumatoid Arthritis with Anti-CD4 Monoclonal Antibodies. 4. Human Monoclonal Autoantibodies. 5. Biologic Therapies for Rheumatoid Arthritis: Concepts from Considerations on Pathogenesis 6. Cellular and Molecular Interactions in the Induction of Inflammation in Rheumatic Diseases. 7. Interleukin-1 Inhibitors and Their Significance in Rheumatoid Arthritis. 8.Interleukins and Metalloproteinases in Arthritis. 9. T Cell Cytokines as Immunomodulators of Arthritis Disease Pathology. 10. Induction and Regulation of Arthritis by T Cell-Derived Collagen Binding Proteins . 11.Experimental Arthritis: Importance of T Cells and Antigen Mimicry in Chronicity and Treatment. 12. A Mycobacterial 65 kd Heat-Shock Protein and T Cells in Experimental Arthritis: Possibilities for Immunotherapy. 13. lmmunotherapy of Collagen-Induced Arthritis with Anti-Ia and Anti-IL-2R Antibodies. 14. Anti-L3T4 Antibody Therapy in Systemic Lupus Erythematosus. 15. Autoreactive B Cells in Collagen-Induced Arthritis. 16. Antiproteoglycan Antibodies in Experimental Spondylarthritis. 17. Reproduction and Regulation of the Autoimmunity That Induces Cartilage Pathology in Experimental Immune Synovitis. 18. Serum Keratan Sulfate Concentration as a Measure of the Catabolism of Cartilage Proteoglycans. Cross-Reactive Idiotypes of Rheumatoid Factors in Arthritis and Related Diseases 20. Characterization of Rheumatoid Factors Using Monoclonal Anti-idiotypic Reagents 21.The Human Anti-DNA ldiotype (16/6 Idiotype) 22. Immunoregulation in Systemic Lupus Erythematosus by Idiotypic Network: Possible Future Therapeutic Implications. 23. Clinical Trial Design and Concepts for Biologic Agents in the Treatment of Rheumatic Diseases

About the Author

Kresina,

Subject Categories

BISAC Subject Codes/Headings:
MED000000
MEDICAL / General
MED014000
MEDICAL / Clinical Medicine
MED083000
MEDICAL / Rheumatology