Monoclonal Antibodies : Cytokines and Arthritis, Mediators of Inflammation and Therapy book cover
1st Edition

Monoclonal Antibodies
Cytokines and Arthritis, Mediators of Inflammation and Therapy

ISBN 9780367402983
Published October 17, 2019 by CRC Press
512 Pages

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Book Description

Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of

Table of Contents

Series Introduction Preface -- 1. Monoclonal Antibodies: New Horizons in the Treatment of Human Autoimmune Disease /William J. Koopman -- 2. Therapeutic Application of Monoclonal Antibodies in the Rheumatic Diseases /Edward V. Lally -- 3. Treatment of Patients with Rheumatoid Arthritis with Anti-CD4 Monoclonal Antibodies /Christian Herzog, Wolfgang Muller, Christoph Walker, and Werner J. Pichler -- 4. Human Monoclonal Autoantibodies /Susan Alpert Gale I, Edgar G. Engleman, and Steven K. H. Foung -- 5. Biologic Therapies for Rheumatoid Arthritis: Concepts from Considerations on Pathogenesis /Ian R. Mackay, Merrill J. Rowley, and Claude C. A. Bernard -- 6. Cellular and Molecular Interactions in the Induction of Inflammation in Rheumatic Diseases /Sharon M. Wahl -- 7 Interleukin-1 Inhibitors and Their Significance in Rheumatoid Arthritis /Gloria C. Higgins and Arnold E. Postlethwaite -- 8. Interleukins and Metalloproteinases in Arthritis /Gene DiPasquale -- 9. T Cell Cytokines as Immunomodulators of Arthritis Disease Pathology /Thomas F. Kresina and Donna J. Spannaus-Martin -- 10. Induction and Regulation of Arthritis by T Cell-Derived Collagen Binding Proteins /David E. Trentham -- 11. Experimental Arthritis: Importance of T Cells and Antigen Mimicry in Chronicity and Treatment /Wim B. van den Berg, Maries F. van den Broek, Levinus B. A. van de Putte, Mieke C. J. van Bruggen, and Peter L. E. M. van Lent -- 12. A Mycobacterial 65 kd Heat-Shock Protein and T Cells in Experimental Arthritis: Possibilities for Immunotherapy /Willem van Eden, Claire J. P. Boog, Els J. M. Hogervorst, Marca H. M. Wauben, Ruurd van der Zee, and Jan D. A. van Embden -- 13. Immunotherapy of Collagen-Induced Arthritis with Anti-la and Anti-IL-2R Antibodies /Paul H. Wooley and Subhashis Banerjee -- 14. Anti-L3T4 Antibody Therapy in Systemic Lupus Erythematosus /Nancy L. Carteron and David Wofsy -- 15. Autoreactive B Cells in Collagen-Induced Arthritis /Rikard Holmdahl -- 16. Antiproteoglycan Antibodies in Experimental Spondylarthritis /Tibor T. Giant, Katalin Mikecz, Edit Buzas, Eric Dayer, and A. Robin Poole -- 17. Reproduction and Regulation of the Autoimmunity That Induces Cartilage Pathology in Experimental Immune Synovitis /Thomas F. Kresina -- 18. Serum Keratan Sulfate Concentration as a Measure of the Catabolism of Cartilage Proteoglycans /Eugene J.-M. A. Thonar, James M. Williams, M. Barry E. Sweet, Brian A. Maldonado, Mary Ellen Lenz, Thomas J. Schnitzer, Giles V. Campion, and Klaus E. Kuettner -- 19. Cross-Reactive Idiotypes of Rheumatoid Factors in Arthritis and Related Diseases /Pojen P. Chen and Dennis A. Carson -- 20. Characterization of Rheumatoid Factors Using Monoclonal Anti-idiotypic Reagents /Mary Ann Accavitti, Ralph E. Schrohenloher, and William J. Koopman -- 21. The Human Anti-DNA Idiotype (16 /6 Idiotype) /Howard Amital-Teplizki and Yehuda Shoenfeld -- 22. Immunoregulation in Systemic Lupus Erythematosus by Idiotypic Network: Possible Future Therapeutic Implications /Nabih /. Abdou and Ronsuke Suenaga -- 23. Clinical Trial Design and Concepts for Biologic Agents in the Treatment of Rheumatic Diseases /Vibeke Strand -- Index.

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Thomas F. Kresina (Author)