Nuclear Magnetic Resonance spectroscopy is a dynamic way for scientists of all kinds to investigate the physical, chemical, and biological properties of matter. Its many applications make it a versatile tool previously subject to monolithic treatment in reference-style texts. Based on a course taught for over ten years at Brandeis University, this is the first textbook on NMR spectroscopy for a one-semester course or self-instruction. In keeping with the authors' efforts to make it a useful textbook, they have included problems at the end of each chapter.
The book not only covers the latest developments in the field, such as GOESY (Gradient Enhanced Overhauser Spectroscopy) and multidimensional NMR, but includes practical examples using real spectra and associated problem sets. Assuming the reader has a background of chemistry, physics and calculus, this textbook will be ideal for graduate students in chemistry and biochemistry, as well as biology, physics, and biophysics. NMR for Physical and Biological Scientists will also be useful to medical schools, research facilities, and the many chemical, pharmaceutical, and biotech firms that offer in-house instruction on NMR spectroscopy.
Table of Contents
1. What Is Spectroscopy?
2. Elementary Aspects of Nuclear Magnetic Resonance (NMR)
3. Elementary Aspects of NMR II: Fourier Transform NMR
4. Nuclear Spin Relaxation and the Nuclear Overhauser Effect
5. Classical and Quantum Descriptions of NMR Experiments in Liquids
6. Density Operator and Product Operator Descriptions of NMR Experiments in Liquids
7. Homonuclear Two-Dimensional NMR Experiments and Coherence Selection
8. Heteronuclear Correlations in NMR
9. Building Blocks for Multidimensional NMR and Special Considerations for Biological Applications of NMR
10. NMR under Anisotropic Conditions: NMR in the Solid State and Ordered Fluids
11. Relaxation Revisited: Dynamic Processes and Paramagnetism
12. Diffusion, Imaging, and Flow
Thomas C. Pochapsky graduated from the University of Pittsburgh with a B.S. in analytical chemistry in 1977. He obtained his PhD in organic chemistry at the University of Illinois, where he met his coauthor. He served post-doctorate positions in biochemistry at the University of Illinois and in macromolecular NMR at Scripps Research Institute in La Jolla, California. Prof. Pochapsky came to Brandeis University in 1989, where he is now a Professor of Chemistry and Protein Structure.
Susan S. Pochapsky graduated with a BA in chemistry from Wayne State University in 1981. She earned her PhD in organic chemistry at the University of Illinois, and did post-doctorate work in NMR of natural products at Scripps Oceanographic Institute. She previously worked as an applications scientist at Bruker Instruments (1990-1996) and a senior research scientist at Harvard-MIT Magnetic Resonance facility (1996-2000), before becoming a senior research associate at Brandeis University.