Nanobiomaterials : Development and Applications book cover
1st Edition

Development and Applications

ISBN 9781138072589
Published March 29, 2017 by CRC Press
490 Pages 220 B/W Illustrations

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Book Description

There is a continuous exchange of ideas taking place at the border of the biological and physical sciences in many areas of nanoscience. Nanotechnology uses biomimetic or bio-inspired processes to produce nanosized materials for applications in biology and other fields. In return, the fruits of nanotechnology are applied to expanding areas of biomedical and therapeutic processes, such as new nanostructures and scaffolds for tissue engineering or targeted drug delivery. In this way, nanobiotechnology serves as a bridge between nano and bio, with nanoscale materials providing the building blocks for the construction of the "bridge." Nanobiomaterials: Development and Applications gives you a broad, interdisciplinary view of current developments as well as new findings and applications in bionanomaterials. The book brings together the work of international contributors who are actively engaged at the forefront of research in their respective disciplines.

Organized into four parts, this book explores the preparation and characterization of nanomaterials, new preparation routes of soft nanomaterials using biomolecules, nano- and microscale hybridization of materials, and nanotoxicity. The contributors cover a diverse set of topics, including:

  • Biomimetic synthesis
  • Bioimaging and cancer diagnosis
  • Photodynamic therapy
  • Bioconjugated carbon nanotube DNA transfection and tumor targeting
  • Magnetically induced hyperthermia
  • Cytotoxity mechanisms and their potential use in therapy
  • Virus-enabled manufacturing of functional nanomaterials
  • Biocatalitic nanosystems and enzyme immobilization
  • Tissue engineering
  • The fabrication of hybrid microswimmers
  • Bionanomaterial applications in environmental remediation

Each chapter is richly illustrated and includes an extensive list of references to guide you toward further research. Combining bionanomaterial development and applications, the book clearly demonstrates the importance of these materials to biotechnology, biomedicine, and environmental remediation. It offers an accessible overview for students, industrial researchers, pharmaceutical innovators, medical and public health personnel, environmental scientists and engineers, and anyone interested in this interdisciplinary field.

Table of Contents

Nanomaterials in Nanobiotechnologies: Preparation, Characterization, and Applications

Bio-Inspired Magnetic Nanoparticles
Georgia C. Papaefthymiou and Eamonn Devlin

Nanoparticles for Bioimaging
Hye Sun Park and Yong Taik Lim

Biomedical Applications of Dendrimer Porphyrin or Phthalocyanine
Woo-Dong Jang and Won-Gun Koh

Polymeric Nanoparticles in Cancer Therapy
Heebeom Koo, Ji Young Yhee, Ick Chan Kwon, Kwangmeyung Kim, and Ramesh Subbiah

Carbon Nanotube Bioconjugates
Monica Samal, Dong Kee Yi, and Shashadhar Samal

Biocatalytic Nanosystems
Jaehong Lim and Su Seong Lee

Magnetically Induced Hyperthermia for Biomedical Applications
Michael Fardis, Ioannis Rabias, Georgios Diamantopoulos, Eleni Karakosta, Danai Tsitrouli, Vassilios Tzitzios, and Georgios Papavassiliou

Soft Block Nanobuilding: New Preparation Routes of Soft Nanomaterials Using Biomolecules

Engineered Biomolecules as Nanomaterials
Yun Jung Lee and Ki Tae Nam

Nanomaterials and Bio-MEMS: Nano- and Microscale Hybridization of Materials and Applications

Microfluidic-Based Polymer Scaffold Design for Tissue Engineering
Mohana Marimuthu and Sanghyo Kim

Fabrication of Mobile Hybrid Microswimmers Using Micro/Nanoparticles and Bacterial Flagella
U. Kei Cheang and Min Jun Kim

Nanotoxicity Studies and Applications in Eco-Biosystems

Environmental Applications of Nanomaterials
Jaesang Lee, Byoung Chan Kim, Hun Je Cho, and Changha Lee

Cytotoxicity of Biosynthesized Nanomaterials and Functionalized Nanomaterials: Use in Therapy
Murugan Veerapandian, Kyusik Yan, Ramesh Subbiah, and Min-Ho Lee


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Dong Kee Yi is a faculty member at the department of bionanotechnology at Gachon University, Korea. Professor Yi serves on the editorial board of ISRN Nanotechnology and reviews for journals from leading scientific societies including the American Chemical Society, Royal Society of Chemistry, and American Institute of Physics. He has authored and coauthored more than 60 peer-reviewed international journal articles and worked as an inventor for 32 international patents. Professor Yi works on research/technology evaluation and advisory panels for the governments of China, Korea, and Romania. He has also worked as a consultant to industrial organizations in Korea.

Georgia C. Papaefthymiou is a professor of physics at Villanova University in Pennsylvania, USA, and a visiting research professor at the National Center for Scientific Research (NCSR) Demokritos in Athens, Greece. She is the author or coauthor of more than 150 publications that include peer-reviewed articles, book chapters, reviews, conference proceedings, and opinion pieces. She is on the board of editors of the Journal of Materials, peer reviewer for multiple physics, chemistry, and materials journals, and grand reviewer for the National Science Foundation and the Department of Energy of the United States and for Aristeia of Greece.


"The topics are very focused yet thorough. The theme of the book is simple and clear, which is the use of nanomaterials for various bio-applications, yet it is thorough in providing detailed discussion from the design and development stage of those nanomaterials to application. Important issues such as the toxicity of these materials are also presented. ... The book maintains a singular focus throughout, a highly advantageous facet not typically seen in other books. The varied topics tie nanomaterials development closely with bioapplication in specific fields, including bioimaging, cancer therapy, and biosensing. Overall, this book was structured in a manner that it could be easily read by anyone interested in the subject, with specific references selected to provide further, more detailed insight into specific topics."
––Timothy Tan, Associate Professor, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore

"The main strength of this book is the consideration of various interdisciplinary aspects of nanobiotechnology such as engineering and surface chemistry aspects involving different nanomaterials. ... This book would be a good reference for graduate students and researchers who are studying or working in the area of nanobiotechnology."
—Nikhil R. Jana, Centre for Advanced Materials, Indian Association for the Cultivation of Science, Kolkata, India

"The book is a comprehensive one which will certainly benefit the students, researchers, scientists, engineers, doctors working in the area of nano and bioscience."
—Assoc. Prof. Subramanian Tamil Selvan, Institute of Materials Research and Engineering

"This book, focused principally on development and application of nanomaterials in the biomedical field, gives an overview on the characterization and preparation of nanoparticles and polymeric matrices assembled and bio-inspired to nature. Written by an international team of experts in biology and chemistry, it emphasizes the need for a more stringent approach to better integrate chemistry, physics and biology for solving the many aspects of the tissue and organs engineering open until today. Offering a good overview on nano-biomaterials as medical devices, drug delivery and tissue engineering systems, the book may be of help not only to specialists on polymer materials, dermatologists, plastic surgeons and clinicians, but also to students in chemistry and medicine and marketing specialists who should like to know more in deep and different interdisciplinary aspects of Nanobiotechnology."
Journal of Applied Cosmetology, July/December 2017