Nanobiomaterials Handbook  book cover
1st Edition

Nanobiomaterials Handbook

Edited By

Balaji Sitharaman

ISBN 9781138076525
Published November 30, 2017 by CRC Press
737 Pages 32 Color & 206 B/W Illustrations

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Book Description

Nanobiomaterials exhibit distinctive characteristics, including mechanical, electrical, and optical properties, which make them suitable for a variety of biological applications. Because of their versatility, they are poised to play a central role in nanobiotechnology and make significant contributions to biomedical research and healthcare. Nanobiomaterials Handbook offers a broad introduction for those new to the subject and serves as a useful reference for advanced professionals.

Analyzing major topics and disciplines in this arena, this volume:

  • Defines scope, current status, and future prospects of nanobiomaterials
  • Surveys nanobiomaterials and examines various synthesis and processing techniques important for developing nanobiomaterials
  • Explores the unique nanoscopic physicochemical properties of nanobiomaterials
  • Discusses potential applications, emphasizing unique challenges in the design, fabrication, and evaluation of biomaterials for a particular application or field
  • Provides a detailed overview of the interactions between bionanomaterials/biological systems and the biocompatibility issues associated with bionanomaterials

Advances in nanobiomaterials requires a multidisciplinary approach spanning major fields in physical and biological sciences, engineering, and medicine with considerable  collaboration between ethicists, regulatory bodies, and industry. This volume brings together the work of a team of world-renowned experts from various fields who discuss the vast potential for nanobiomaterials in a myriad of applications.

Table of Contents

Nanobiomaterials: Current and Future Prospects; Pramod K. Avti, Sunny C. Patel,Balaji Sitharaman

Multifunctional Gold Nanoparticles for Cancer Therapy; Maung Kyaw Khaing Oo, Henry Du,Hongjun Wang

Synthesis, Processing, and Characterization of Ceramic Nanobiomaterials for Biomedical Applications; Michael Hacker, Rudi Hötzel, Peter-Georg Hoffmeister, Michaela Schulz-Siegmund

Synthesis, Properties, Characterization, and Processing of Polymeric Nanobiomaterials for Biomedical Applications; Theoni K. Georgiou

Carbon-Based Nanomedicine; Michael L. Matson, Jeyrama Anantha, and Lon J. Wilson

Synthetic and Toxicological Characteristics of Silica Nanomaterials for Imaging and Drug Delivery Applications; Heather Herd,Hamid Ghandehari

Peptide-Based Self-Assembled Nanofibers for Biomedical Applications; Joel M. Anderson, Meenakshi Kushwaha, Dong Jin Lim, and Ho-Wook Jun

Electrostatically Self-Assembled Nanomaterials; Helmut Strey

Peptide-Based Nanomaterials for siRNA Delivery: Design,

Evaluation, and Challenges; Seong Loong Lo, Yukti Choudhury,Shu Wang

Nucleic Acid Nanobiomaterials; Bin Wang

Emerging Technologies in Nanomedicine; Debra T. Auguste, F. Kyle Satterstrom, Marjan Rafat, Jin-Oh You

Nanomaterials for Therapeutic Drug Delivery; Dinesh Jegadeesan and M. Eswaramoorthy

Nanobiomaterials for Nonviral Gene Delivery; Xiujuan Zhang, Daniel A. Balazs, W.T. Godbey

Nanobiomaterials for Cancer-Targeting Therapy; Mingji Jin, Zhonggao Gao

Nanobiomaterials for Ocular Applications; Rinti Banerjee

Nucleic Acid Based Nanobiosensing; Nicholas M. Fahrenkopf, Phillip Z. Rice and Nathaniel C. Cady

Nanobiomaterials for Molecular Imaging; Dian Arifin and Jeff Bulte

Gadolinium-Based Bionanomaterials for Magnetic Resonance Imaging; Eva Toth and Lothar Helm

Nanostructured Materials for Improved Magnetic Resonance Imaging; Hamsa Jaganathan, Albena Ivanisevic

Nanobiomaterials for Dual-Mode Molecular Imaging: Advances in Probes for MR/Optical Imaging Applications; Chuqiao Tu and Angelique Louie

Nanoscale Probes for the Imaging of RNA in Living Cells; Philip J. Santangelo, Aaron Lifland, Chiara Zurla

Nanomaterials for Artificial Cells; Xiaojun Yu, Elvin Lee, Alicia Vandersluis, Harinder K. Bawa

Nanobiomaterials for Musculoskeletal Tissue Engineering; Minal Patel, Kyobum Kim, and John P. Fisher

Nanocomposite Polymer Biomaterials for Tissue Repair of Bone and Cartilage: A Material Science Perspective; Akhilesh K. Gaharwar, Patrick J. Schexnailder, Gudrun Schmidt

Collagen: A Natural Nanobiomaterial for High-Resolution Studies in Tissue Engineering; Brian M. Gillette, Niccola N. Perez, Prasant Varghese, Samuel Sia

Nanotopography on Implant Biomaterials; Edwin Lamers, Frank Walboomers, and John Jansen

Nanoarray Bionanotechnology; Alexandra H. Brozena and YuHuang Wang

Photopatternable Multifunctional Nanobiomaterials; Tingrui Pan, Hailin Cong

Nanobiomaterials for Preclinical Studies and Clinical Diagnostic; Youssef Zaim Wadghiri, Karen Briley-Saebo

Biocompatibility of Nanomaterials: Physical and Chemical

Properties of Nanomaterials Relevant to Toxicological Studies, In

Vitro and In Vivo; Christie Sayes and J. Michael Berg

Hemocompatibility of Nanoparticles; Shankar J. Evani, Anand Ramasubramanian

Breaking the Carbon Barrier: Nanobiomaterials and Communal

Ethics; David M. Berube


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Balaji Sitharaman is an assistant professor of biomedical engineering at Stony Brook University in New York. He received his BS (2000) from the Indian Institute of Technology, Kharagpur, and his MA and PhD (2005) from Rice University, Houston, Texas, where he also completed his postdoctoral research (2005–2007) as the J. Evan Attwell-Welch Postdoctoral Fellow at the Richard E. Smalley Institute for Nanoscale Science and Technology. Sitharaman’s research program is at the interface of nanotechnology, regenerative, and molecular medicine, and synergizes the advancements in each of these fields to tackle problems related to diagnosis/treatment of disease and tissue regeneration. He has authored over 50 publications and has eight patents. He has received several awards for his research, including NIH Director’s New Innovator Award from the National Institute of Health, the Idea Award from the Department of Defense, the Carol M. Baldwin Breast Cancer Research Award from the Carol Baldwin Foundation, and the George Kozmetsky Award from the Nanotechnology Foundation of Texas.