1st Edition

Nanobiomaterials Handbook

Edited By Balaji Sitharaman Copyright 2011
    737 Pages 32 Color & 206 B/W Illustrations
    by CRC Press

    764 Pages 32 Color & 206 B/W Illustrations
    by CRC Press

    Nanobiomaterials exhibit distinctive characteristics, including mechanical, electrical, and optical properties, which make them suitable for a variety of biological applications. Because of their versatility, they are poised to play a central role in nanobiotechnology and make significant contributions to biomedical research and healthcare. Nanobiomaterials Handbook offers a broad introduction for those new to the subject and serves as a useful reference for advanced professionals.

    Analyzing major topics and disciplines in this arena, this volume:

    • Defines scope, current status, and future prospects of nanobiomaterials
    • Surveys nanobiomaterials and examines various synthesis and processing techniques important for developing nanobiomaterials
    • Explores the unique nanoscopic physicochemical properties of nanobiomaterials
    • Discusses potential applications, emphasizing unique challenges in the design, fabrication, and evaluation of biomaterials for a particular application or field
    • Provides a detailed overview of the interactions between bionanomaterials/biological systems and the biocompatibility issues associated with bionanomaterials

    Advances in nanobiomaterials requires a multidisciplinary approach spanning major fields in physical and biological sciences, engineering, and medicine with considerable  collaboration between ethicists, regulatory bodies, and industry. This volume brings together the work of a team of world-renowned experts from various fields who discuss the vast potential for nanobiomaterials in a myriad of applications.

    Nanobiomaterials: Current and Future Prospects; Pramod K. Avti, Sunny C. Patel,Balaji Sitharaman

    Multifunctional Gold Nanoparticles for Cancer Therapy; Maung Kyaw Khaing Oo, Henry Du,Hongjun Wang

    Synthesis, Processing, and Characterization of Ceramic Nanobiomaterials for Biomedical Applications; Michael Hacker, Rudi Hötzel, Peter-Georg Hoffmeister, Michaela Schulz-Siegmund

    Synthesis, Properties, Characterization, and Processing of Polymeric Nanobiomaterials for Biomedical Applications; Theoni K. Georgiou

    Carbon-Based Nanomedicine; Michael L. Matson, Jeyrama Anantha, and Lon J. Wilson

    Synthetic and Toxicological Characteristics of Silica Nanomaterials for Imaging and Drug Delivery Applications; Heather Herd,Hamid Ghandehari

    Peptide-Based Self-Assembled Nanofibers for Biomedical Applications; Joel M. Anderson, Meenakshi Kushwaha, Dong Jin Lim, and Ho-Wook Jun

    Electrostatically Self-Assembled Nanomaterials; Helmut Strey

    Peptide-Based Nanomaterials for siRNA Delivery: Design,

    Evaluation, and Challenges; Seong Loong Lo, Yukti Choudhury,Shu Wang

    Nucleic Acid Nanobiomaterials; Bin Wang

    Emerging Technologies in Nanomedicine; Debra T. Auguste, F. Kyle Satterstrom, Marjan Rafat, Jin-Oh You

    Nanomaterials for Therapeutic Drug Delivery; Dinesh Jegadeesan and M. Eswaramoorthy

    Nanobiomaterials for Nonviral Gene Delivery; Xiujuan Zhang, Daniel A. Balazs, W.T. Godbey

    Nanobiomaterials for Cancer-Targeting Therapy; Mingji Jin, Zhonggao Gao

    Nanobiomaterials for Ocular Applications; Rinti Banerjee

    Nucleic Acid Based Nanobiosensing; Nicholas M. Fahrenkopf, Phillip Z. Rice and Nathaniel C. Cady

    Nanobiomaterials for Molecular Imaging; Dian Arifin and Jeff Bulte

    Gadolinium-Based Bionanomaterials for Magnetic Resonance Imaging; Eva Toth and Lothar Helm

    Nanostructured Materials for Improved Magnetic Resonance Imaging; Hamsa Jaganathan, Albena Ivanisevic

    Nanobiomaterials for Dual-Mode Molecular Imaging: Advances in Probes for MR/Optical Imaging Applications; Chuqiao Tu and Angelique Louie

    Nanoscale Probes for the Imaging of RNA in Living Cells; Philip J. Santangelo, Aaron Lifland, Chiara Zurla

    Nanomaterials for Artificial Cells; Xiaojun Yu, Elvin Lee, Alicia Vandersluis, Harinder K. Bawa

    Nanobiomaterials for Musculoskeletal Tissue Engineering; Minal Patel, Kyobum Kim, and John P. Fisher

    Nanocomposite Polymer Biomaterials for Tissue Repair of Bone and Cartilage: A Material Science Perspective; Akhilesh K. Gaharwar, Patrick J. Schexnailder, Gudrun Schmidt

    Collagen: A Natural Nanobiomaterial for High-Resolution Studies in Tissue Engineering; Brian M. Gillette, Niccola N. Perez, Prasant Varghese, Samuel Sia

    Nanotopography on Implant Biomaterials; Edwin Lamers, Frank Walboomers, and John Jansen

    Nanoarray Bionanotechnology; Alexandra H. Brozena and YuHuang Wang

    Photopatternable Multifunctional Nanobiomaterials; Tingrui Pan, Hailin Cong

    Nanobiomaterials for Preclinical Studies and Clinical Diagnostic; Youssef Zaim Wadghiri, Karen Briley-Saebo

    Biocompatibility of Nanomaterials: Physical and Chemical

    Properties of Nanomaterials Relevant to Toxicological Studies, In

    Vitro and In Vivo; Christie Sayes and J. Michael Berg

    Hemocompatibility of Nanoparticles; Shankar J. Evani, Anand Ramasubramanian

    Breaking the Carbon Barrier: Nanobiomaterials and Communal

    Ethics; David M. Berube



    Balaji Sitharaman is an assistant professor of biomedical engineering at Stony Brook University in New York. He received his BS (2000) from the Indian Institute of Technology, Kharagpur, and his MA and PhD (2005) from Rice University, Houston, Texas, where he also completed his postdoctoral research (2005–2007) as the J. Evan Attwell-Welch Postdoctoral Fellow at the Richard E. Smalley Institute for Nanoscale Science and Technology. Sitharaman’s research program is at the interface of nanotechnology, regenerative, and molecular medicine, and synergizes the advancements in each of these fields to tackle problems related to diagnosis/treatment of disease and tissue regeneration. He has authored over 50 publications and has eight patents. He has received several awards for his research, including NIH Director’s New Innovator Award from the National Institute of Health, the Idea Award from the Department of Defense, the Carol M. Baldwin Breast Cancer Research Award from the Carol Baldwin Foundation, and the George Kozmetsky Award from the Nanotechnology Foundation of Texas.