1st Edition

Nanocarriers for Nucleic Acids and Proteins

Edited By Luis H. Reyes, Juan C. Cruz, Yashwant V. Pathak Copyright 2025
418 Pages 50 Color & 2 B/W Illustrations
by CRC Press

At the frontier of modern medicine lies a revolution in drug delivery systems that operates at the scale of billionths of a meter. Nanocarriers for Nucleic Acids and Proteins presents a comprehensive exploration of these groundbreaking technologies that are reshaping therapeutic approaches across medical science. From fundamental concepts to cutting-edge applications, this comprehensive... Read more

Chapter 1: Introduction to Nanocarriers for Nucleic Acids and Proteins.                

Juan C. Cruz, Yashwant V Pathak, and Luis H. Reyes

 

Chapter 2: Design Principles of Nanocarriers: Size, Shape, and Surface Properties, Stimuli-Responsive Systems.

Juan C. Cruz and Luis H. Reyes

 

Chapter 3: Lipid-Based Nano Carriers for Nucleic Acids and Proteins: Liposomes, solid lipid nanoparticles, nanostructured lipid carriers

Biswajit Basu, Ayon Dutta, Dipanjana Ash, Bhupendra Prajapati, and Swarupananda Mukherjee

 

Chapter 4:  Polymer-based nanocarriers: dendrimers, polymeric  micelles, hydrogels

Juan C. Cruz and Luis H. Reyes

 

Chapter 5: Inorganic nano carriers: gold nanoparticles, iron nanoparticles, silica nanoparticles, quantum dots

Juan C. Cruz and Luis H. Reyes

 

Chapter 6: Carbon-based nano carriers: Carbon nanotubes, graphene oxide, fullerenes, and Carbon dots

Cristian F. Rodríguez, Paula Guzmán-Sastoque, Coryna Rodriguez-Bazurto, Juan C. Rojas-Hernández, Luis H. Reyes, and Juan C. Cruz  

 

Chapter  7 : Virus Inspired Nano Carriers

Ankita Alice Singh and Seema Kohli

 

Chapter  8: Nucleic acid nano carriers DNA nanostructures, RNA  nanostructures, hybrid nucleic acid systems

Komal Parmar and  Jayvadan Patel

 

Chapter  9 : Protein-based nano carriers: protein cages, self-assembling peptides, fusion proteins,

Nishant B. Chopade, Prashant K. Deshmukh, and Mahesh P. More

 

Chapter  10 : Nanocarrier Functionalization Strategies: Targeting Ligands, Imaging Agents, stimuli-responsive Elements

Sampada Satish Shinde, Bhavna Sonule, and Lalit Kumar

 

Chapter  11: Delivery of nucleic acids using nano carriers: siRNA and miRNA delivery, mRNA and DNA delivery, CRISPR-Cas systems

Paula Guzmán–Sastoque, María Camila Monsalve, Cristian F. Rodríguez, Stiven Castellanos, Juan C. Cruz, and  Luis H. Reyes

 

Chapter  12: Delivery of proteins using nanocarriers: enzymes, antibodies and growth factors

Jennifer Suurbaar, Frederick Sarfo-Antwi, and Seth Kwabena Amponsah

 

Chapter  13 : Nanocarrier in gene therapy

Sinjini Sarkar, Swarupananda Mukherjee, Shilpa Chatterjee, Biswajit Basu, Dipanjan Karati, and Bhupendra Prajapati

 

Chapter  14: Nanocarriers in Cancer Immunotherapy: Personalized Cancer Vaccines, Immune Checkpoint Modulation, Adoptive T-Cell Therapy

Vineet Mahajan and Yashwant Pathak

 

Chapter 15: Future perspectives and challenges: clinical translation and regulatory aspects, scale-up and manufacturing, ethical considerations

Aparoop Das, Kalyani Pathak, Riya Saikia, Manash Pratim Pathak, Urvashee Gogoi, Dibyajyoti Das, Jon Jyoti Sahariah, Saptasikha Gogoi, and  Sukanya Sonowa

 

Chapter 16: Regulatory Toxicology of Biologics: Safeguarding Health in  Biotherapeutic Development

Kinjal Parikh, Nishant Talati, Shahin Vhora, Nidhi Kotadiya, Mitul Talala, Ruby Chrisitan, Vikas Jain, Tosha Pandya, Disha Suthar, and Satish Rojekar

Biography

Luis H. Reyes, PhD, is an associate professor at Universidad de Los Andes (Bogotá, Colombia), where he leads research at the intersection of biological engineering and therapeutic delivery systems. He holds a BS in Chemical Engineering from Universidad Industrial de Santander (Colombia) and a PhD in Chemical Engineering from Texas A&M University.

Juan C. Cruz, PhD, is a distinguished researcher and engineer at the Department of Biomedical Engineering, Universidad de Los Andes (Bogotá, Colombia), where he has been advancing the frontiers of nanobiotechnology since 2016. He holds a BS in Chemical Engineering from the National University of Colombia and earned his PhD in Chemical Engineering from Kansas State University, where his innovative work established a new platform for enzyme immobilization for applicstions in non-aqueous media.

Yashwant V. Pathak received his PhD from Nagpur University, India, Executive MBA and Masters in Conflict Management, Sullivan University, Louisville, KY, USA. He has over 45 years’ experience in Academia and Industry. Presently, he is Professor and Associate Dean for Faculty Affairs at Taneja College of Pharmacy, University of South Florida, Tampa, FL, USA. Yashwant has published over 400 research papers, reviews and chapters with close to 5000 citations in Google Scholar. He edited over 70 books in nanotechnology, nutraceuticals, drug delivery systems, artificial intelligence, and artificial neural network. He has keen interest in conflict management and edited several books in the areas of organizational conflict management, handbook of organizational conflict management, Eastern and Indigenous perspectives in conflict management, RSS way of resolving conflicts and these two volumes on nonprofit organizations’ conflict management.