This book offers a fundamental and comprehensive overview of nanomedicine from a systems engineering perspective, making it the first book in the field of quantitative nanomedicine based on systems theory. The book starts by introducing the concept of nanomedicine and provides basic mathematical modeling techniques that can be used to model nanoscale biomedical and biological systems. It then demonstrates how this idea can be used to model and analyze the central dogma of molecular biology, tumor growth and the immune system. Broad applications of the idea are further illustrated by Bayesian networks, multiscale and multiparadigm modeling and AFM engineering.
Table of Contents
Nanomedicine — Dynamic Integration of Nanotechnology with Biomedical Science
Fundamental Mathematical Modeling Techniques for Nano Biosystem
A Mathematical Formulation of the Central Dogma of Molecular Biology
Systems Approach to Characterize Living Drosophila Embryos for Biomedical Investigations
Learning Signaling Pathway Structure
Computational Modeling of Tumor Biobarriers: Implications for Delivery of Nano-based Therapeutics
Multiscale-Multiparadigm Modeling and Simulation of Nanometer-Scale Systems and Processes for Nanomedical Applications
Game Theoretical Formulation of the Immune System and Inspiration for Controlled Drug Delivery Application
Mingjun Zhag, Ning Xi
"Taking a unique, systems perspective, this book not only covers fundamental information on nanomedicine, but also provides an account of modeling, simulation, and experimental tools for dealing with challenges at the interface between nanotechnology and medicine. It is an excellent reference for researchers and students in this burgeoning field."
—Xiaobo Tan, Michigan State University, USA