1st Edition

Nanomedicine for Neurodegenerative Disorders Selective Treatment Strategies

Edited By Rishabha Malviya, Kamla Pathak, Swati Verma Copyright 2025
524 Pages 53 B/W Illustrations
by Apple Academic Press

524 Pages 53 B/W Illustrations
by Apple Academic Press

With the population getting older and with a corresponding increase in neurodegenerative diseases (NDs) worldwide, developing drug delivery systems that can overcome conventional barriers in treating these diseases is the need of the hour. Drug delivery by nanotechnology has great promise for detecting and treating a wide range of neurodegenerative conditions. This new book provides an informative... Read more

1. Neurodegenerative Disorders: Concepts, Types, and Treatment Strategies

Chandana Majee, Rupa Mazumder, and Bhawani Pantela

2. Overview of the Blood-Brain Barrier (BBB) Transport Mechanisms

Shilpa Verma, Mahesh Gaikwad, Gajanan Paul, and A. K. Yadav

3. Nanodiamonds as Emerging Nanotherapeutics for Brain-Targeted Drug Delivery in the Management and Diagnosis of Neurodegenerative Disorders

Bhagawati Saxena, Fagun Pathak, Bhavna Bohra, and Viral Shah

4. The Real Issue in Targeting Neurodegenerative Disease

Smriti Ojha, Anubhav Ananad, Hina Chadha, and Sudhanshu Mishra

5. Strategies to Cross the Blood-Brain Barrier

Shraddha Dwivedi

6. Nanotechnology-Based Drug Delivery Systems for the Treatment of Neurodegenerative Disorders

Himanshu Paliwal, Bhupendra G. Prajapati, and Teerapol Srichana

7. Nano Approaches Towards CNS Drug Delivery

Ashwani Sharma, Anjali Sharma, Girish Kumar, Tarun Virmani, and Kamla Pathak

8. Current Trends in Drug-Nano Formulations Directed to the Brain

Dignesh Khunt, Brijesh Shah, Smit Nayi, Akshay Parihar, and Bhupendra Prajapati

9. Selection of an Appropriate Technique for Nano-Carrier Preparation: A Multi-Criteria Decision-Making Methodology

Pankaj Sharma

10. Delivery of RNA/DNA to the Brain Using Nanoscience

Akanksha Sharma, Ashish Verma, Aditi Singh, and Rishabha Malviya

11. Application of Medicinal Plants and Their Phytoconstituents Used in the Management of Neurodegenerative Diseases

Padmini Shukla and Prabodh Shukla

12. Molecular Mechanisms Underpinning Neuroprotection of Nutritional Polyphenols

Johnson O. Oladele, Isaac O. Babatunde, and Oluwaseun T. Oladele

13. Implication of Herbal Nano-Formulations in the Treatment of Neurological Disorders

Sunny R. Shah, Vijay R. Chidrawar, Prashant L. Pingale, Sudarshan Singh, Bhupendra Prajapati, and Devang Sheth

14. Medical Laboratory Diagnosis of Neurodegenerative Diseases Toward Adequate Treatment in Nanomedicine

Uchejeso Mark Obeta, Amaechi Eze Odono, Nkereuwem Sunday Etukudoh, and Obiora Reginald Ejinaka

15. Role of Biomarkers in Detection, Diagnosis, and Prognosis of Neurodegenerative Disorders

Ruchi Singh, Ankita Moharana, Srishti Tiwari, Soubhik Bhattacharyya, Garima Tripathi, and Dhanalekshmi Unnikrishnan Meenakshi

16. Use of Nano-Formulations in the Treatment of Neurodegenerative Disorders

Ujjwal Gupta, Suryawanshi Ajay, Farhan Mazahir, and A. K. Yadav

17. Nanostructured Drug Carriers for Nose-to-Brain Drug Delivery in the Treatment of Neurological Disorders

Noopur Srivastava, Pawan Upadhyay, Alka Srivastava, Shibu Das, and Sudhanshu Mishra

Biography

Rishabha Malviya, PhD, is Associate Professor of Pharmacy at the School of Medical and Allied Sciences at Galgotias University, Uttar Pradesh, India. He has authored more than 150 research and review papers for national and international journals of repute. He holds over 50 patents and has edited 13 books and authored 15 book chapters. His name has been included in the World's Top 2% Scientists list by Elsevier BV and Stanford University. He is reviewer, editor, and editorial board member of more than 50 national and international journals.

Kamla Pathak, PhD, is Dean and Professor of Pharmacy at Uttar Pradesh University of Medical Sciences, Etawah, India. With teaching and research experience of more than 30 years, she has received many awards for her work. She has over 270 publications in journals of international and national repute. She also holds three patents and has authored four books and more than 20 book chapters. Professor Pathak has served as a member of the editorial advisory board of AAPS Pharm Sci Tech and is also a member of various professional bodies. She is also associated with the Indian pharmaceutical industry in the capacity of a scientific consultant. She has been listed in the top 2% of Indian scientists of the subsection Pharmacology and Pharmacy, in the World's Top 2% Scientists list.

Swati Verma, MPharm, is working in the Department of Pharmacy at the School of Medical and Allied Sciences, Galgotias University, Uttar Pradesh, India. Her areas of interest are in computer-aided drug design, analytical chemistry, targeted drug delivery, and nanoformulation. She has authored four book chapters, edited two books, and many review papers published in international journals. She completed a BPharm at Dr. A.P.J. Abdul Kalam Technical University and MPharm (Pharmaceutical Chemistry) at Banasthali Vidyapith, Rajasthan, India. Her PhD work is in neurodisorders.

“This book will be helpful for healthcare professionals in treating neurodegenerative disorders. It will give
readers profound insights into the recent uses of several cutting-edge nanocarriers that contain active
pharmaceutical ingredients for the effective treatment of illnesses connected to neurons.”

—From the Foreword by Dr. Brahmeshwar Mishra, Professor and Former Head, Department of
Pharmaceutical Engineering and Technology, IIT, Uttar Pradesh, India

“4 stars / score: 91. Provides an informative overview of the cutting-edge applications of various nanocarriers that encapsulate active compounds to effectively treat NDs. . . . This book is genuinely forward-thinking in the field of nanomedicine and neurodegenerative diseases. It is a high-quality resource for healthcare practitioners and scientists in drug research and development that serves as a detailed reference as well as a look into the future of therapies for neurodegenerative and similar disorders. I absolutely recommend this book in academic settings, for researchers pursuing neuropharmacology or nanotherapeutics drug design and development, and for clinicians who want a deeper understanding of where treatment innovation is heading.”

—Doody’s Review Service (DRS), Jan 2026; reviewed by Chidinma Onukogu, PharmD, BCACP (Department of Veterans Affairs, USA)