1st Edition

Nanoparticles in Cancer Therapy Innovations and Clinical Applications

Edited By Neelam Thakur, Bhukya Prudhvi Lal Copyright 2025
344 Pages 97 Color & 1 B/W Illustrations
by CRC Press

344 Pages 97 Color & 1 B/W Illustrations
by CRC Press

This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines... Read more

Part I:  Nanoparticles in Cancer Vaccines and Gene Therapy

Chapter 1.1. Polymeric nanoparticles as nanovaccine carriers for eliciting   anticancer immunity

Hardeep Kaur, Shinar Athwal, Sakshi Thakur, Prudhvilal Bhukya and Neelam Thakur

Chapter 1.2. Membrane-Based Nano-Vaccines for Immunotherapy

Harsha Sharma and Sakshi Thakur

Chapter 1.3. Gene Therapy Utilizing Nanoparticles

Radhika Jamwal

Part II: Advanced Nanomedicine Approaches

Chapter 2.1 From Diagnosis to Treatment: The Role of Chemodynamic Nanoparticles in Cancer Theranostics

Akriti Sharma, Arundhati, Manmeet Kaur, Vishal Sharma, Md Zia ul Haq andDisha Sharma Chapter 2.2 Low-Dimensional Nanomaterials as an Emerging Platform for Cancer Diagnosis and Therapy

Karan Mehta, Shamli Rajput and Surbhi Sharma

Chapter 2.3. Emerging Nano-based Strategies for Managing Drug Resistance in Cancer

Priyanka Chambial, Neelina Jaggarwal and Neelam Thakur

Chapter 2.4 Nanotechnology-based Radiation Therapy to Cure Cancer

Bhupender Sahu, Janvi Sharma, Bibhudendu Behera, Umesh Kumar

Chapter 2.5.Phototherapy Modalities Empowered by Nanotechnology

Nisha Kumari and Vishav Gaurav Singh Chandel

Chapter 2.6. Bioengineered Virus-Like Nanoparticles for Cancer Diagnostics and Therapeutics

Anupam Bhardwaj

Part III: Clinical Applications and Future Prospects

Chapter 3.1. Theranostic Nanoparticles: Revolutionizing Cancer Diagnosis and Treatment

Gagandeep Singh, Himanshu, Umesh Kumar and Neelam Thakur

Chapter 3.2.Anti-Cancer Nanotherapeutics in Clinical Trials: The Work Behind Clinical Translation of Nanomedicine

Priyanka Chambial, Neelam Thakur, L.Preethi  and Pankaj Mehta

Chapter 3.3. Limitations of Cancer Nanotherapy: Present Status and Future Prospects

Navya Rana, Sunil Kumar and Ranjit Kumar

Chapter 3.4. Current Challenges and Future Prospects in Nanoparticle Application

Anuradha Derashri, Nitin Kolhe.  Divya Dhawal Bhandari and Akanksha Dwivedi

Chapter 3.5. Assessment of Genotoxicity and Immunotoxicity Nanoparticles: Overview and testing methods

Rishabh Mittal, Aditi Agarwal, Shivashish Dobhal, Jitender Gairolla and

 Manisha Naithani

Chapter 3.6.Assessment of Nanoparticles Induced Cytotoxicity and Safety Profiles

Devyani Rajput, Akanksha Dwivedi, Anuradha Derashri, Divya Dhawal Bhandari and Nitin Kolhe

Chapter 3.7. Nanotechnology in Cancer Therapy: Targeted Drug Delivery and the Role in Viral Oncogenesis

Darsh Gautam, Gaurav Joshi, Poonam Talwan and Preeti Bisht

Biography

Prudhvi Lal Bhukya is a Virologist currently serving at ICMR-National Animal Resource Facility for Biomedical Research (NARFBR), Hyderabad, as a Scientist. Presently, he is associated with the preclinical vaccine testing laboratory at NARFBR. His areas of work include preclinical vaccinology studies, hostviral interaction studies of emerging human viral infections, and the prevention and control of diseases, as well as the development of tools to prevent outbreaks. He obtained his Ph.D. from ICMR-National Institute of Virology, Pune, on human hepatitis B virus. He proved his credentials by working on HBV and HEV with an extensive publication record. He has presented his work at numerous national and international conferences and has received accolades with several publications in international journals like the Journal of General Virology, Journal of Virology, Journal of Travel Medicine, Indian Journal of Medical Microbiology and Science of Total Environment. He is an experienced manuscript writer and has contributed to several book chapters for publication bodies like Springer Nature, CRC Press, IntechOpen, IGI Global Publications, etc. Dr. Prudhvi also edited a book in Springer Nature entitled “Emerging Human Viral Disease” in two volumes. His contribution to these books as an editor will act as a catalyst, as his comments are highly critical and an achievement for the book.

Neelam Thakur is currently working as an Assistant Professor in the Department of Zoology at Sardar Patel University (a State Govt. University), Mandi, Himachal Pradesh, India since 2022. Before joining this university, she worked as an Associate Professor in the Department of Biosciences at Chandigarh University, Punjab, India. She obtained her Ph.D. in Genetics from Himachal Pradesh University in 2012. After her Ph.D., she joined as a Research Associate in the Immunology lab of CSIR-IMTECH, Chandigarh in 2012. Her research interests include the early diagnosis of tuberculosis and cancer, nanotechnology for cancer diagnostics and therapy, cytogenetic analysis of intellectually disabled individuals and microbiome studies. She has supervised many master’s students and is currently guiding Ph.D. students as well. She has published 18 research papers in journals with good impact factors, such as “Cellular Signaling”. Her patent, entitled “ANTIGENIC COMPOSITION AND METHOD OF EXPRESSION THEREOF”, was also published. She has received two Young Researchers Awards and one Eminent Researchers Award from government-registered societies/ organizations for her contribution to research.