This book presents the state-of-the-art advances and applications of nanozymes, the recently developing branch of enzymology that synthesizes and uses nanomaterials that mimic the function of traditional enzymes. During the past decade, the study of nanozymes has grown rapidly. Several new nanomaterials that exhibit enzymatic actions have been identified, along with new applications for their practical use. This book draws upon the work of experts from around the world and provides an in-depth analysis and cutting-edge overview of nanozymes, with an eye toward their present and future applications.
Chapters are arranged in a logical order to provide physio-chemical characterization of nanozyme and basic mechanisms of their enzymatic actions. Focusing on current limitations of nanozymes and their reaction kinetics, the book presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. It also focuses on traditional and novel nanozyme applications, such as biosensing, drug delivery, and disease therapy, as well as their use as antibacterials. An important addition in this book is the summary of emerging literature on nanozyme toxicology.
This book is intended as a ready reference for advanced undergraduate and graduate students doing research in nanotechnology; materials science; chemistry; and chemical, biological, biomedical, and food engineering. Research and development scientists, engineers, and technologists working in the chemical and biological/biomedical industries will gain much from the materials in this book for their industry practice.
- Presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness.
- Discusses metal organic frameworks as nanozymes.
- Reviews on traditional and novel nanozyme applications, such as biosensing, drug delivery, disease therapy, and their use as antibacterials.
- Examines nanozyme toxicology.
Dr. Sundaram Gunasekaran is a Professor in the Department of Biological Systems Engineering at the University of Wisconsin–Madison.
Table of Contents
1. Enzymes – Inspiring Evolutionary Wisdom
José I. Reyes De Corcuera
2. Nanozymes – An Overview
Loghman Alaei, Zhila Izadi, Samira Jafari, Alireza Lotfabadi, Ebrahim Barzegari, Mehdi Jaymand and Hossein Derakhshankhah
3. Metal Oxide Nanozymes
Biwu Liu and Juewen Liu
4. Noble Metal Nanozymes
Chunxia Li, Weilin Chen, Yulin Xie, Man Wang
5. Glucose Oxidase-mimicking Nanozymes
Atul Sharma, Swapnil Tiwari, Jean Louis Marty
6. Bioaffinity-based Nanozymes
Çiğdem Kip, Kadriye Özlem Hamaloğlu, Ali Tuncel
7. Nanozymes in Biosensing and Bioimaging
Syed Rahin Ahmed, Ana Gomez Cardoso, Satish Kumar, Greter A. Ortega, Seshasai Srinivasan, Amin Reza Rajabzadeh
8. Gold Nanozymes in Therapeutics
Smriti Singh, Seema Nara
9. Nanozymes in Electrochemical Analysis
Cem Erkmen, Sevinc Kurbanoglu, Bengi Uslu
10. Nanozymes as Photothermal-Catalytic Agents
Xianwen Wang, Xiaoyan Zhong, Haisheng Qian, Zhengbao Zha
11. Nanozymes in Detecting Environmental Pollutants
Xin Li, Peng Liu, Mengzhu Wang, Xiangheng Niu
12. Nanozymes in Pesticides Detection
Mai Luo, Ting Wang, Ling Chen, Zehua Cheng, Sundaram Gunasekaran, Jinchao Wei, Peng Li
13. DNAzymes in Food and Environmental Contaminants Detection
Kaiyu He, Liu Wang, Xiahong Xu
14. Nanozymes in Food Contaminants Analysis
15. Nanozymes in Food Science and Technology
Lunjie Huang, Da-Wen Sun
16. Rational Design of Peroxidase Nanozymes
Xiaoyu Wang, Hui Wei
17. Potential Toxicology of Nanozymes
Weizheng Wang, Sundaram Gunasekaran
Dr. Sundaram Gunasekaran is a professor in the Department of Biological Systems Engineering at the University of Wisconsin-Madison.