Natural Products in Drug Discovery Benefits, Challenges, and Opportunities

Preface

1. Natural Products as Drug Candidates

Tooba Mahboob, Mogana Sundari Rajagopal, and Saad Tayyab

2. Traditional Knowledge for Drug Discovery

Tamanna, Kuldipika Sharma, Sanjeev Kumar, Neeraj Sankhyan, Yash Pal Sharma, Nitin Sharma, and Meenakshi Thakur

3. Herbal Healing: Plant-Based Natural Products

Anchal Sharma and Meenakshi Thakur

4. Natural Products with Antimicrobial Properties

María Melissa Gutiérrez Pacheco, Heriberto Torres Moreno, Ricardo Salomon Torres, Luis Alberto Ortega Ramírez, and Julio César López Romero

5. Natural Products with Immunomodulatory Properties

Rashim Kumari, Shriya Bhatt, Mahesh Gupta, and Rajat Rana

6. Natural Products with Anticancer Properties

Nidhee Chaudhary, Ogireddy Sri Apoorva, and Mansi Agrawal

7. Natural Products with Antiviral Properties

Maria Carolina Jasso Miranda

8. Approaches to Develop Drugs from Natural Products

Himani Sharma, Shivani Chauhan, Kavita Rana, and Preeti Sharma

9. Strategies for Isolation and Identification of Bioactive Molecules from Natural Sources

Hamid, Deepika Kathuria, Sunakshi Gautam, Shakshi Sharma, and Shweta Suri

10. Role of Omics in Natural Products-Based Drug Discovery

Bhagyabhumi Shah, Ruchi Yadav, Nilay Solanki, and Bhumika Patel

11. Natural Products from Endophytic Microorganisms

David C. Nwobodo and Peter M. Eze

12. Natural Products with Antidiabetic Properties

Kanchan Singh

13. Marine-Derived Natural Products with Anticancer Properties

Popat Mohite, Ramdas Pandhare, and Deshraj Chumbhale

14. Natural Products as Novel Opportunities for Cathepsin Inhibitors

Emerson Finco Marques

15. Phytoestrogens in Drug Discovery: A Focus on Mechanisms of Action and Safety Assessment

Bancha Yingngam

16. Honey Bee Products with Antimicrobial Properties

Jelena Ćirić and Tatjana Baltić

17. Natural Products for the Prevention of Leaky Gut

Devi Basumatary, Pranamika Sarma, and Jagat C. Borah

18. Role of Natural Products in the Pharmacotherapy of Osteoporosis

Raja Chakraverty, Somoshree Sengupta, and Tatini Debnath

19. Gel-Based Natural Therapeutics: Potential Alternatives to Traditional Drug Delivery Systems in Aquaculture

Suparna Deb, Bhavesh Choudhary, Jham Lal, Pradyut Biswas, Soibam Khogen Singh, and Gusheinzed Waikhom

20. The Promising Role of Natural Products as Neuroprotective Agents

Ajaykumar Chittipolu, Nunavath Raja Shekhar, and Nimmala Shanthi

21. Natural Products from Microbes

Sharon Nagpal, Lenika Kashyap, Sanjula Sharma, Pooja, and Jomika Devi

22. Natural Product Databases: Discovering Nature's Riches

Gaurav Kumar, Pankaj Barman, Rituraj Konwar, and Ravindra K. Rawal

23. Bioprospecting and Commercialization of Natural Products

Pankaj Barman, Gaurav Kumar, Kallol Roy, Ravindra K. Rawal, and Rituraj Konwar

Index

Biography

Meenakshi Thakur, PhD, is an Assistant Professor (Biochemistry) at Dr. Yashwant Singh Parmar University of Horticulture and Forestry, Hamirpur, Himachal Pradesh, India. Dr. Thakur's research interests and contributions are on biotic and abiotic stress management in plants by employing various strategies such as use of elicitors/plant-based extracts or essential oils. She has published research and review articles and book chapters. She was awarded an INSPIRE fellowship from the Department of Science & Technology (India) in 2011 for her doctorate research. She has won prestigious awards from the Association of Indian Universities, New Delhi, India, and received an honorable jury mention certificate in the young scientist category by EET CRS (Educational Training and College Rating System), India. She received a travel grant from the Houghton Trust and British Poultry Science for participation at the 20th Congress of the World Veterinary Poultry Association at Edinburgh, Scotland. Dr. Thakur serves as an academic editor for PLOS One and is also a recognized reviewer for several journals.