Neurodegeneration Molecular Basis of Treatment Approaches

1. Introduction to Neurodegeneration: Molecular Basis of Treatment Approaches

Ankita Kashyap and Rajashri Bezbaruah

2. Neurodegeneration: Etiology, Epidemiology, Diagnosis

Niva Rani Gogoi, Krupa Vyas, Payal Dodiya, and Vivek P. Chavda

3. Molecular Mechanisms of Neurodegenerative Diseases

Dignesh Khunt, Megha Patel, and Ravi Patel

4. Protein Folding and Misfolding in Neurodegenerative Diseases

Rutvi J. Vaidya, Arya S. Vyas, Pankti C. Balar, Dixa A. Vaghela, Harshid Kukadiya, and Vivek P. Chavda

5. Biomarkers Studies in Neurodegenerative Disease

Pankti C. Balar, Rajashri Bezbaruah, Bibhuti Bhushan Kakoti, Gautam Saxena, Sneha Paul, Payal Dodiya, and Vivek P. Chavda

6. Oxidative Stress in Neurodegeneration: Cause or Consequence?

Lakshyajeet Nath, Chayanika Kalita, Dixa A. Vaghela, and Bibhuti B. Kakoti

7. Neurodegeneration with Brain Iron Accumulation

Rasmita Khatonier, Simran Kaur, Zonunmawii, Hasmi Waris, and Bibhuti B. Kakoti

8. Approved Treatment Strategies for Neurodegenerative Diseases

K. Sandhanam, Bedanta Bhattacharjee, T. Tamilanban, Ram Kumar Sahu, Ajayi Ayodeji Folorunsho, and Rajashri Bezbaruah

9. Unlocking the Potential: Repurposing Drugs for Neurodegeneration

Kangkan Deka, Tutumoni Kalita, Bhargab Thakuria, Renaldy Donlang Nongbet, Iman Bhaduri, Gitima Deka, and Vivek P Chavda

10. Use of AI/ML for Diagnosis and Treatment

Niva Rani Gogoi, Venessa Nath, Arka Karmakar, Pinky Chowrasia, Vivek P. Chavda, and Bhaskar Mazumder

11. Ethnomedical Contributions Toward Neurodegenerative Diseases

Damanbhalang Rynjah, Bedanta Bhattacharjee, Ram Kumar Sahu, Jiyauudin Khan, Vivek P. Chavda, and Rajashri Bezbaruah

12. Advanced CRISPR/Cas and Genetic Approaches for Neurodegeneration

Anup Kumar, Pooja Pandita, Pankti C. Balar, and Vivek P. Chavda

13. Challenges and Future Prospects in the Diagnosis and Treatment of Neurodegenerative Diseases

Vivek P. Chavda, Damanbhalang Rynjah, Nasima Ahmed, Pankti C. Balar, and Rajashri Bezbaruah

Biography

Vivek P. Chavda, MPharm, is an Assistant Professor in the Department of Pharmaceutics and Pharmaceutical Technology at L. M. College of Pharmacy, India. Before joining academia, he worked in the biologics industry in research and development, contributing to regulatory filings at Lupin Biotech and Dr. Reddy's Laboratories. He has more than 200 publications to his credit. He is listed among the world's top 2% of scientists by Stanford University and Elsevier. His interests include biologics process and formulation development, medical device development, nano-diagnostics, non-carrier formulations, long-acting parenteral formulations, and nano-vaccines.

Rajashri Bezbaruah, MPharm, is a Lecturer at the Institute of Pharmacy, Assam Medical College and Hospital, India. She was formerly affiliated with the Pratiksha Institute of Pharmaceutical Sciences and the Department of Pharmaceutical Sciences at Dibrugarh University, India. To her credit, she has more than 18 national and international publications, five book chapters, and eight articles in progress. Her research interests include immunological studies, evaluation of herbal neuroprotective drugs, and extraction and isolation of herbal drugs.

Bibhuti Bhushan Kakoti, PhD, is a Professor of Pharmaceutical Sciences at Dibrugarh University, India, where he is also the in-charge for the Centre of Studies in Biotechnology, scientist in-charge of the Institutional Animal Ethical Committee, and member of various boards. He has guided more than 20 PhD scholars and has published more than 40 national and international articles and book chapters. His research interests include screening and evaluation of plants and synthetic drugs.

Vladimir N. Uversky, PhD, DSc, FRSB, FRSC, is a Professor in the Department of Molecular Biology, University of South Florida, USA. He has authored over 1150 scientific publications and has been included on the Clarivate List of Highly Cited Researchers™ from 2014 to 2020. He is a Fellow of the Royal Society of Biology and a Fellow of the Royal Society of Chemistry. He has delivered more than 240 invited talks and seminars around the globe and has collaborated with more than 12,500 colleagues from more than 2,750 research organizations in 89 countries/territories. He is an editor of a number of scientific journals and has edited several books and book series on protein structure, function, folding, and misfolding.