1st Edition
New Drugs, Fair Prices Managing the Pharmaceutical Innovation Ecosystem for Sustainable and Affordable New Medicines
Preface: Writing with Intent
Acknowledgements
- Balancing Tomorrow with Today
- A New Paradigm for a Wicked Problem
- The Discovery Habitat
- The Innovation Habitat
- The Coalition Habitat
- The Value Habitat
- The Pricing Habitat
- The Competition Habitat
- The Patient Habitat
- Breaking Ground, Raising the Debate
Precis
How important a question is this?
How American a question is this?
First, do no harm. What might change put at risk?
Does pharmaceutical innovation have a problem?
Where does this leave us?
Precis
Why did the drug pricing debate become so sterile?
Are we looking at drug pricing the wrong way?
What is the case for the ecosystem paradigm?
What is the pharmaceutical innovation ecosystem?
What does the ecosystem perspective imply for the affordability debate?
The pharmaceutical innovation ecosystem is fragile
The pharmaceutical innovation ecosystem can only be managed systemically
How can we resolve our dilemma?
Precis
What is the discovery habitat and who inhabits it?
What does a healthy PIE require of the discovery habitat?
Is the discovery habitat capable of supporting a healthy PIE?
How can we improve the discovery habitat?
Will this be enough?
Precis
What happens in the innovation habitat and who inhabits it?
What does a healthy PIE require of the innovation habitat?
Is the innovation habitat capable of supporting a healthy PIE?
How can we improve the innovation habitat?
Will this be enough?
Precis
What happens in the coalition habitat and who inhabits it?
What does a healthy PIE require of the coalition habitat?
Is the coalition habitat capable of supporting a healthy PIE?
How can we improve the coalition habitat?
Will this be enough?
Precis
What happens in the value habitat and who inhabits it?
What does a healthy PIE require of the value habitat?
Is the value habitat capable of supporting a healthy PIE?
How can we improve the value habitat?
Will this be enough?
Precis
What happens in the pricing habitat and who inhabits it?
What does a healthy PIE require of the pricing habitat?
Is the pricing habitat capable of supporting a healthy PIE?
How can we improve the pricing habitat?
Will this be enough?
Precis
What happens in the competition habitat and who inhabits it?
What does a healthy PIE require of the competition habitat?
Is the competition habitat capable of supporting a healthy PIE?
How can we improve the competition habitat?
Will this be enough?
Precis
What happens in the patient habitat and who inhabits it?
What does a healthy PIE require of the patient habitat?
Is the patient habitat capable of supporting a healthy PIE?
How can we improve the health of the patient habitat?
Will this be enough?
Precis
Where are we now?
Breaking ground on a PIE for the future
Raising the debate
Index
Biography
Brian D. Smith is an academic, author and advisor who has worked in and studied the life sciences sector for over 40 years. He has published over 300 books, papers and articles and worked with most of the world’s leading pharmaceutical companies.
