Based on presentations made during the 6th International Symposium on Natural Product Chemistry, this book is divided into two sections. Section A has articles on synthetic routes developed to complex natural products, whilst Section B is a compilation of discoveries of new natural products and their pharmacological properties. There are several chapters in this volume devoted to advances in the quest for improved anticancer agents from natural resources - be they plants, marine organisms or micro-organisms. Additionally, approaches to the development of antimalarial agents are reviewed, as are strategies for cancer chemopreventive agents.
Table of Contents
Part 1 Open chain 1,3-stereocontrol: synthetic studies on anti-tumor alkaloids; synthetic studies in the alkaloid field - synthesis of epibatidine; synthetic studies on antitumor antibiotics and enzyme inhibitors; epoxy sulfonate pyranoses, valuable intermediates in carbohydrate syntheses. Part 2 Recent studies on biologically active natural products: novel strategies for the discovery of plant-derived anticancer agents; discovery and characterization of natural product cancer chemopreventive agents; logical approach to structure elucidation of natural compounds; new natural products from indigenous medicinal plants; bioactive compounds fom the leaves and pods of moringa oleifera; new alkaloids and biological activities of Turkish amaryllidiceae plants; malarial vaccine candidate - the nature of the carbohydrate-peptide linkage in the 42-53 KDA glycoprotein; effect of the imidazoline compounds on sympathomimetic responses and its pharmacological implications. (Part contents).
Atta-ur Rahman, M.Iqbal Choudhary, HEJ Research Institute of Chemistry, University of Karachi, Pakistan