1st Edition

Nonclinical Drug Administration Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems

By Shayne C. Gad, Charles B. Spainhour Copyright 2018
420 Pages 11 B/W Illustrations
by CRC Press

420 Pages 11 B/W Illustrations
by CRC Press

If we will ever achieve Paul Ehrlich’s "magic bullet," that is, a molecule which goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body, the practice of safety assessment will have to change. Nonclinical Drug Administration: Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems seeks... Read more

Pharmacotherapy, Toxicodynamics and Regulatory Science—Divergent Objectives

Nonclinical Pharmacokinetics - a primer

Routes - with considerations for species specificity

Delivery Systems

Regimens

Fundamentals of Nonclinical Formulation

Excipients and Vehicles: Tolerance and toxicity

Appendices

Biography

Shayne C. Gad, Charles B. Spainhour