1st Edition
Novel Approaches in Metronomic Chemotherapy for Breast Cancer Treatment
This book provides the latest research and developments in the field of metronomic chemotherapy for breast cancer. It presents the principles and mechanisms of metronomic chemotherapy, preclinical and clinical studies, and the latest developments in drug delivery systems and nanoformulations. The clinical pharmacology of metronomic chemotherapy, including pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions, are also examined.
Key Features:
- Introduces metronomics therapy in the neoadjuvant and adjuvant treatment of breast cancer
- Explores the potential of metronomics in terms of personalized chemotherapy
- Present pharmacological bases of metronomic chemotherapy
- Covers the latest developments in drug delivery systems, nanotechnology, and nanoformulations
- Discusses antiangiogenic effects and the impact of metronomics on immunity
This book is useful for students, researchers, oncologists, pharmacologists, and healthcare experts interested in understanding the clinical potential of metronomic chemotherapy in breast cancer.
Chapter 1 Introduction to metronomic chemotherapy
Manzoor Ahmad Mir, Nusrat Jan, and Shazia Sofi
Chapter 2 Metronomic chemotherapy- a multi-targeted therapy
Manzoor A. Mir, Aisha Shabir and Burhan Ul Haq.
Chapter 3 Conventional chemotherapeutic vs. metronomic chemotherapy
Manzoor A. Mir, Nusrat Jan and Hina Qayoom
Chapter 4 The anti-angiogenic basis of metronomic chemotherapy
Manzoor A. Mir, Asma Jan, Aisha Shabir and Burhan Ul Haq.
Chapter 5 Imaging techniques, biomarkers, and methods for metronomic chemotherapy
Manzoor A. Mir, Tabish Javeed, Aisha Shabir, and Nusrat Jan.
Chapter 6 Metronomic chemotherapy in breast cancer
Manzoor A. Mir, Aisha Shabir, and Nusrat Jan.
Chapter 7 Metronomic chemotherapy in combination with anticancer vaccines
Manzoor A. Mir, Tabish Javeed, and Burhan Ul Haq.
Chapter 8 Metronomic: towards personalized chemotherapy
Manzoor A. Mir, Asma Jan, Aisha Shabir, and Nusrat Jan.
Chapter 9 Metronomic chemotherapy for metastatic breast cancer
Manzoor A. Mir, Burhan Ul Haq, Mary Chatterjee, Kirti Hooda.
Chapter 10 Recent Advances, challenges, and future of metronomic chemotherapy
Manzoor A Mir, Sania Bashir, Shristi Handa, and Mary Chatterjee.
Chapter 11 Targeted therapies in combination with metronomic chemotherapy
Manzoor A. Mir, Fatima Manhas, Kirti Hooda, and Mary Chatterjee.
Chapter 12 Recent advances in metronomic chemotherapy: nanotechnology-based low-dose chemotherapy in breast cancer
Manzoor A. Mir, Burhan Ul Haq, Nasreen Rashid.
Index
Biography
Dr. Manzoor Ahmad Mir holds Master’s Degree in Zoology with Gold Medal from HNBG Central University and after qualifying prestigious National level CSIR-JRF-NET examination; he worked jointly for his PhD at Jawaharlal Nehru University New Delhi and CSIR-Institute of Microbial Technology Chandigarh in the field of Immunopathology. His basic research interests include, molecular immunology and Immunobiology of microbes (MTB). His PhD research title was “Role of co-stimulation in the survival of intracellular pathogens”. He currently teaches Cancer Biology, and Immunology at the Department of Bioresources, School of Biological Sciences, University of Kashmir. He is presently heading the Department of Bioresources, University of Kashmir.