1st Edition

Novel Drug Delivery Systems in the Management of Chronic Diseases

    430 Pages 12 Color & 35 B/W Illustrations
    by Apple Academic Press

    Novel Drug Delivery Systems in Management of Chronic Diseases covers recent trends of NDDS in context with the most frequently occurring chronic diseases. The book details recent developments in research on drug delivery systems and addresses many problems arising as a result of conventional approaches.

    The volume covers the fundamental aspects of chronic diseases in conjunction with NDDS, where the authors have detailed the usefulness of NDDS in the management of chronic diseases and outlined the different materials that can help prepare NDDS with desired properties. Chapters also look at NDDS applications for central nervous system (CNS) diseases, including Alzheimer’s and Parkinson’s.

    The book goes on to address NDDS with HIV and cancer, two fatal diseases, covering recent trends to target these two major diseases. Chapters provide detailed information on the usefulness of NDDS in diabetes, asthma and respiratory complications, and diabetic retinopathy. Chapters also look at the use of NDDS in herbal drug delivery, the involvement of artificial intelligence in development of NDDS, and more.

    This new volume provides an informative overview of the current scope of NDDS for chronic diseases as well as its future development, including how artificial intelligence can be used in novel formulations. The book will prove useful for research scholars and researchers.

    PART I: FUNDAMENTALS OF CHRONIC DISEASES

    1. Overview on Chronic Diseases

    Neelam L. Dashputre, Umesh D. Laddha, Eknath D. Ahire, Deepti D. Bandawane, Surabhi B. Patil, and Jayesh D. Kadam

    2. Overview on NDDS (Novel Drug Delivery System) for the Betterment of Chronic Diseases

    Kamlesh D. Mali, Nikita S. Kumawat, and Vivek S. Kumawat

    3. Insight to Suitable Polymers and Materials for Preparation of NDDS

    Amit Vitthal Kakad, Layba Sajjadali Sayyad, Pooja Shankar Niphade, Bhadane Roshani Giridhar, Anuja Shivaji Nalkar, Umesh Dilip Laddha, and Sanjay J. Kshirsagar

    PART II: NOVEL DRUG DELIVERY SYSTEM IN CNS DISEASES

    4. Novel Drug Delivery Systems for Treatment of Chronic Alzheimer’s

    Abhijeet Kulkarni, Vishal Gulecha, Pravin Jha, Amar Zalte, Ramdas Dolas, Sushil Narkhede, Sumit Deore, Akshada Kothule, Vivek Wagh, Mayur More, and Vishal Pande

    5. Parkinson’s Targeting: A Novel Drug Delivery Approach

    Sapana P. Ahirrao, Deepak S. Bhambere, Sanjay J. Kshirsagar, and Jayesh D. Kadam

    6. Nose-to-Brain Delivery as a Novel Drug Delivery System

    Smita P. Kakad, Sanjay J. Kshirsagar, Chetan Sonawane, Milind Shewale, and Rushikesh Shinde

    PART III: NOVEL DRUG DELIVERY SYSTEM FOR FATAL DISEASE

    7. Novel Drug Delivery Systems in the Treatment of Cancer: A Better Future Hope

    Nitin R. Shirsath, Mahesh P. More, Prashant K. Deshmukh, Vishal S. Bagul, Jayvadan K. Patel, Bhavesh V. Bhavsar, and Prashant B. Patil

    8. Novel Drug Delivery Systems in HIV/AIDs and Associated Complications

    Deepak S. Bhambere, Varsha Chaudhari, Sapana P. Ahirrao and Sanjay J. Kshirsagar

    9. Novel Drug Delivery Systems for Diabetes: An Immense Hope

    Gowtham Menon, Sachin Gaikwad, Deepak Pisote, Rohit Choure, Girish A. Kashid, and Raosaheb S. Shendge

    10. Novel Drug Delivery Systems in the Management of Asthma and Pulmonary Diseases

    Mangesh A. Bhutkar, Dheeraj S. Randive, Somnath D. Bhinge, Ganesh H. Wadkar, and Chandrakantsing V. Pardeshi

    11. New Frontiers for the Management of Diabetic Retinopathy

    Umesh D. Laddha, Kailas K. Moravkar, Eknath D. Ahire, and Sanjay J. Kshirsagar

    PART IV: NOVEL DRUG DELIVERY SYSTEM AND FUTURE ASPECTS

    12. Artificial Intelligence for a New Era of NDDS

    Rohan K. Barse

    Biography

    Raj K. Keservani, PhD, is currently working as Associate Professor, Faculty of B. Pharmacy, CSM Group of Institutions, Prayagraj, India. He has more than 12 years of academic (teaching) experience at various institutes in India. He has published more than 50 book chapters, over 25 edited books, several co-authored books, and over 30 peer-reviewed papers in the field of pharmaceutical sciences in national and international journals. He is also active as a reviewer for several international scientific journals. He has supervised more than 25 undergraduate students for their research work. He has a patent under his name as well. Dr. Keservani is a life member of the Society of Pharmaceutical Education and Research. His research interests include nutraceutical and functional foods, novel drug delivery systems (NDDS), transdermal drug delivery/drug delivery, health science, cancer biology, and neurobiology. Dr. Keservani graduated with a pharmacy degree from the Department of Pharmacy, Kumaun University, Nainital (Uttarakhand), India. He received his Master of Pharmacy (MPharm) (specialization in pharmaceutics) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, India. He received his PhD degree from IKG Punjab Technical University, Jalandhar, Punjab, India.

    Umesh D. Laddha, MPharm, is currently working as an Assistant Professor in the Department of Pharmaceutics at MET’s, Institute of Pharmacy, Bhujbal Knowledge City, Adgoan, Nashik, affiliated to Savitribai Phule Pune University, Pune, India. He has eight years of academic experience and is an editor board member of the International Journal of Ophthalmology, Visual Science (USA), and Asian Journal of Pharmaceutical Research (India). He is also working as a reviewer for various journals published by Springer and Elsevier. He is author of several books and book chapters. He has published more than 15 research and review articles in well-reputed national and international journals. He has one patent to his credit along with two others in progress. He has also received several awards including Young Scientist Award (bronze medal), Researcher of the Year, Best Teacher Award, and many more. He has presented research work at various international and national conferences. He has worked on nanotechnology-based drug delivery systems and novel drug delivery systems. He graduated with a BPharm and master’s degree from Savitribai Phule Pune University, Pune, India, where he is currently pursuing a PhD.

    Eknath D. Ahire, MSPharm, is currently working as an Assistant Professor in the Department of Pharmaceutics at MET’s, Institute of Pharmacy, Bhujbal Knowledge City, Adgoan, Nashik, affiliated to Savitribai Phule Pune University, Pune, India. He is also working for QCS Labs LLP, Mumbai, as Inspector for Nigeria regulatory market pre-shipment inspection under the Earn and Learn Scheme. He has a total of five years of experience as Formulation Scientist II at Torrent Research Centre, Gandhinagar, Gujrat, as well as four years of academic experience. He is also a reviewer for several reputed international journals, including Pharmaceutical Development and Technology (Taylor and Francis), International Journal of Applied Nanotechnology Research (IGI Global), and Exploration of Immunology Journal. He is an editorial board member of the journals Acta Scientific and Community Acquired Infection. He is life member of the Association of Pharmaceutical Teachers of India. He has more than 30 publications (research, review, and book chapters) in national and international indexed journals as well as six textbooks. He has participated and attended several national and international conferences and workshops. He has worked on nanotechnology-based novel drug delivery systems, nutraceuticals, and immunology. He graduated with a BPharm degree from Savitribai Phule Pune University and master’s degree (MS Pharm) in Pharmaceutics from the National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A), India. Currently, he is admitted as a PhD Scholar with Savitribai Phule, Pune University, India. He was awarded a NFST (RGNF) PhD Research Scholar fellowship by the Government of India.

    Sanjay J. Kshirsagar, PhD, is working as Professor and Principal at MET’s, Institute of Pharmacy, Bhujbal Knowledge City, Adgoan, Nashik, affiliated to Savitribai Phule Pune University, Pune, India. He has more than 19 years of experience in the pharmaceutical field. He has guided 50 MPharm students and is currently in charge of eight PhD students. He has published more than 160 research and review articles in well-reputed national/international journals with a cumulative impact factor of 70. He has been awarded with several awards, including Best Research Guide by national-level Pharma Innova, Best Original Paper Award, Pharma Excipients Poster Award from the International AG, and many more. He is acting as member of the board of studies in pharmaceutics of Savitribai Phule Pune University, Pune, and Inspector of the Pharmacy Council of India, India. He has one patent under his name with four others under progress. He has authored many books and book chapters. In addition, he has presented more than 20 papers in national and international conferences. He is also an expert in colon targeted drug delivery system. He completed his PhD at JNTU, Hyderabad, India.