Nutritional Oncology : Nutrition in Cancer Prevention, Treatment, and Survivorship book cover
1st Edition

Nutritional Oncology
Nutrition in Cancer Prevention, Treatment, and Survivorship

ISBN 9781032002613
Published August 23, 2021 by CRC Press
520 Pages 17 Color & 10 B/W Illustrations

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Book Description

Nutritional Oncology: Nutrition in Cancer Prevention, Treatment, and Survivorship presents evidence-based approaches to the study and application of nutrition in all phases of cancer including prevention, treatment, and survivorship.

There is a long history of interest in the role of nutrition in cancer but only in the last 50 years has this interdisciplinary field developed scientific evidence from a combination of population studies, basic research, and clinical studies. Precision oncology, targeted  therapies and immunonutrition have led to advances in cancer treatment and prevention. Highlighting insights from Precision Oncology and Precision Nutrition to improve cancer prevention, treatment and survival is the core mission of this book. The editors have over 40 years of clinical and research experience integrating science with practical advice based on available evidence for healthcare professionals while highlighting research vistas for the scientific community.


  • Comprehensive treatment of all aspects of nutrition and cancer, including prevention, response to treatment, avoidance of relapse and promotion of quality of life for cancer survivors.
  • Examines alternative medicines and botanical dietary supplements and identifies hypotheses for future research based on science.

This book is written for doctors, dietitians, and other health care professional advising cancer patients, cancer survivors and the general public.

Table of Contents

Part 1. Fundamentals of Human Nutrition and Cancer Metabolism 

1. Historical Evolution of the Role of Nutrition in Cancer 

David Heber and Vay Liang W. Go

2. Cancer Metabolism and Nutrition 

David Heber

3. Precision Oncology and Precision Nutrition 

John A Glaspy, Sidharth R. Anand and David Heber

4. Phytonutrients and Cancer 

David Heber and Navindra Seeram

5. Nutrition and Immune Function 

Emily Truong and Berkeley N. Limketkai

6. Personalized Nutrition and Cancer 

David Heber and Zhaoping Li

Part 2. Nutrition and Carcinogenesis 

7. Epidemiology of Nutrition, Diet, and Cancer Risk 

David Heber, Qing-Yi Lu and Zuo-Feng Zhang 

8. Oxidant Stress and Carcinogenesis 

Susanne Henning

9. Nutrition, Angiogenesis, and Cancer 

William W. Li

10. Cholesterol and Prostate Cancer 

Smrruthi V. Venugopal, Shafiq A. Khan, Stephen F. Freedland et al.

11. The Microbiome and Cancer  

David Heber and Zhaoping Li

12. Exercise, Energy Balance, Body Composition, and Cancer Risk

Catherine L. Carpenter

13. Nutrition, Hormones, Cancer Risk and Progression 

David Heber and Zhaoping Li

Part 3. Nutritional Recommendations for Cancer Patients 

14. Nutrition Support for Cancer Patients throughout the Continuum of Care 

Refaat Hegazi, Katie N. Robinson, Bridget Cassady et al.

15. Malnutrition and Cancer Cachexia 

David Heber and Zhaoping Li

16. Nutrition and Chemotherapy in the Epidemic of Obesity 

Rebecca L. Paszkiewicz and Steven D. Mittelman

17. Integrative Oncology and Nutrition    

David Heber and Zhaoping Li

Part 4. Care of the Cancer Survivor 

18. Susceptibility to Common Age-Related Chronic Diseases 

Lauren Lemieux and Zhaoping Li

19. Nutritional Advice and Dietary Supplements for the Cancer Survivor 

Michael Garcia and David Heber

20. Lifestyle Changes and Behavioral Approaches for the Cancer Survivor

William McCarthy and Catherine Carpenter

Part 5. Challenges in Nutritional Oncology Research 

21. Environmental Factors in Cancer Risk 

Lishi Xie and Gail S. Prins

22. Minority Health Disparities in Nutrition and Cancer 

Keith Norris, Bettina M Beech and David Heber

23. The Critical Questions in Nutrition and Cancer that Remain  

David Heber and Zhaoping Li

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Dr. Heber is Professor Emeritus of Medicine and Public Health at the David Geffen School of Medicine at UCLA and is internationally prominent in the field nutrition and cancer as well as in obesity, and age-related chronic diseases and the application of nutrition in common forms of cancer including prostate and breast cancer. He is also the Founding Director of the UCLA Center for Human Nutrition and founding Chief of the Division of Clinical Nutrition in the UCLA Department of Medicine where he directed multiple NIH-funded research programs including the National Cancer Institute-funded UCLA Clinical Nutrition Research Unit, The NIH-funded UCLA Dietary Supplements Research Center: Botanicals and the NIH- National Institutes of Diabetes, Digestive, and Kidney Diseases UCLA Nutrition and Obesity Training Program where he oversaw the training of research fellows many of whom are currently in academic or industry positions. He has published over 250 research papers and numerous professional texts.  Internationally. In 2014, he co-wrote a textbook with Dr. Bharat Aggarwal entitled “Immunonutrition” (CRC Press).  Dr. Heber is board-certified in Internal Medicine, and Endocrinology and Metabolism by the American Board of Internal Medicine. He earned his MD at Harvard Medical School, and his Ph.D. in Physiology at the University of California, Los Angeles. In 2014, he was elected a Fellow of the American Society for Nutrition, the highest honor of the society. In 2017, he co-wrote a textbook for doctors together with Dr. Zhaoping Li, entitled “Primary Care Nutrition: Writing the Nutrition Prescription (CRC Press, 2017).


Zhaoping Li, MD, PhD is the Lynda and Stewart Resnick Endowed Chair in Human Nutrition, Professor and Chief of the Division of Clinical Nutrition in the Department of Medicine at the David Geffen School of Medicine at UCLA.  She is also the Vice Chair of Medicine at the Greater Los Angeles VA Health System and is the Director of the multidisciplinary UCLA Center for Human Nutrition which includes the renowned UCLA Weight Management Program, the Nutritional Medicine Consultation Service and a Nutritional Oncology Consultation Program serving cancer patients in over 80 practices within UCLA Health Care System.  She has been working with Dr. Heber in the Division of Clinical Nutrition since 1997.  Dr. Li is board certified in internal medicine, physician nutrition specialists, a fellow of American College of Physicians, and is a former President of the National Board of Physician Nutrition Specialists and a member of the Board of Directors of the American Society for Nutrition.  Her research interests span both basic and clinical research in obesity, cancer and other age-related chronic diseases and she supervises a faculty of MD clinical physician scientists and PhD laboratory scientists investigating gene-nutrient interaction, nutritional modulation of the microbiome, and health impacts of phytonutrients. Dr. Li has been a principal investigator for over 100 investigator-initiated National Institutes of Health and industry-sponsored clinical trials and published over 200 peer-reviewed scientific papers. In addition to the present volume she co-wrote “Primary Care Nutrition: Writing the Nutrition Prescription” with Dr. David Heber, published by CRC Press in 2017.


Vay Liang W. Go, M.D. is a distinguished professor and co-director of the UCLA Agi Hirshberg Center for Pancreatic Diseases at the David Geffen School of Medicine at UCLA, Editor-in-Chief of Pancreas and co-founder of the American Pancreatic Association. Over a five-decade academic career, his research has focused on the regulation of the human exocrine and endocrine pancreas and gut-brain axis in health and disease. He expanded to nutrition and cancer prevention and the mechanism of action of phytochemicals on pancreatic diseases utilizing metabolomics technologies. He received his internal medicine and gastroenterology training and subsequently became a professor of medicine at the Mayo Clinic. From 1985 to 1988, Dr. Go served in three related capacities at the National Institutes of Health, all involving digestive diseases and nutrition. He became the Executive Chairman, UCLA Department of Medicine from 1988-1992. In 1994, he co-founded the UCLA Center for Human Nutrition with Dr. David Heber. He was the Associate Director of the NCI-funded Clinical Research Unit, director of the Nutrition Education program and co-principal investigator of the NIH funded nutrition curriculum development grants and the cancer prevention curriculum program. Dr. Go has authored and co-authored more than 400 peer reviewed manuscripts and mentored and trained more than 80 fellows in the field of gastroenterology, nutrition, endocrinology, and pancreatology, many of whom have attained leadership roles in their respective fields.