1st Edition

OMICS Applications in Biomedical, Agricultural, and Environmental Sciences

Edited By Debmalya Barh, Vasudeo Zambare, Vasco Azevedo Copyright 2013
    718 Pages 97 B/W Illustrations
    by CRC Press

    713 Pages 97 B/W Illustrations
    by CRC Press

    With the advent of new technologies and acquired knowledge, the number of fields in omics and their applications in diverse areas are rapidly increasing in the postgenomics era. Such emerging fields—including pharmacogenomics, toxicogenomics, regulomics, spliceomics, metagenomics, and environomics—present budding solutions to combat global challenges in biomedicine, agriculture, and the environment. OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences provides valuable insights into the applications of modern omics technologies to real-world problems in the life sciences. Filling a gap in the literature, it offers a broad, multidisciplinary view of current and emerging applications of omics in a single volume.

    Written by highly experienced active researchers, each chapter describes a particular area of omics and the associated technologies and applications. Topics covered include:

    • Proteomics, epigenomics, and pharmacogenomics
    • Toxicogenomics and the assessment of environmental pollutants
    • Applications of plant metabolomics
    • Nutrigenomics and its therapeutic applications
    • Microalgal omics and omics approaches in biofuel production
    • Next-generation sequencing and omics technology for transgenic plant analysis
    • Omics approaches in crop improvement
    • Engineering dark-operative chlorophyll synthesis
    • Computational regulomics
    • Omics techniques for the analysis of RNA splicing
    • New fields, including metagenomics, glycomics, and miRNA
    • Breast cancer biomarkers for early detection
    • Environomics strategies for environmental sustainability

    This timely book explores a wide range of omics application areas in the biomedical, agricultural, and environmental sciences. Throughout, it highlights working solutions as well as open problems and future challenges. Demonstrating the diversity of omics, it introduces readers to state-of-the-art developments and trends in omics-driven research.

    The World of Omics and Applications in Biomedical Sciences

    Proteomics: Techniques, Applications, and Challenges
    Namasivayam Elangovan

    Epigenome: Genomic Response to Environmental Eccentricities
    Anjana Munshi, Srirama Krupanidhi, and Yog Raj Ahuja

    Epigenomics: Basics and Applications
    Jaspreet Kaur and Jyotdeep Kaur

    Pharmacogenomics for Individualized Therapy
    Eugenia Ch. Yiannakopoulou

    Pharmacogenomic Knowledge to Support Personalized Medicine: The Current State
    Casey Lynnette Overby and Houda Hachad

    Toxicogenomics: Techniques, Applications, and Challenges
    Indra Arulselvi Padikasan and Nancy Daliel

    The World of Noncoding RNAs
    Winnie Thomas, Qurratulain Hasan, Konagurtu Vaidyanath, and Yog Raj Ahuja

    Spliceomics: The OMICS of RNA Splicing
    Atmakuri Ramakrishna Rao, Tanmaya Kumar Sahu, and Nishtha Singh

    Computational Regulomics: Information Theoretic Approaches toward Regulatory Network Inference
    Vijender Chaitankar, Debmalya Barh, Vasco Azevedo, and Preetam Ghosh

    Glycomics: Techniques, Applications, and Challenges
    Veeraperumal Suresh, Chinnathambi Anbazhagan, and Dakshanamurthy Balasubramanyam

    Breast Cancer Biomarkers
    Rajneesh K. Gaur

    Use of Protein Biomarkers for the Early Detection of Breast Cancer
    Birendra Kumar, Purnmasi Ram Yadav, and Surender Singh

    The World of Omics and Applications in Plant and Agricultural Sciences

    Genomics, Proteomics and Metabolomics: Tools for Crop Improvement under Changing Climatic Scenarios
    Hifzur Rahman, D.V.N. Sudheer Pamidimarri, Ramanathan Valarmathi, and Raveendran Muthurajan

    Application of Next-Generation Sequencing for Abiotic Stress Tolerance
    Tapan Kumar Mondal and Keita Sutoh

    Next-Generation Sequencing and Assembly of Bacterial Genomes
    Artur Silva, Rommel Ramos, Adriana Carneiro, Sintia Almeida, Vinicius De Abreu, Anderson Santos, Siomar Soares, Anne Pinto, Luis Guimarães, Eudes Barbosa, Paula Schneider, Vasudeo Zambare, Debmalya Barh, Anderson Miyoshi, and Vasco Azevedo

    Towards Engineering Dark-Operative Chlorophyll Synthesis Pathways in Transgenic Plastids
    Muhammad Sarwar Khan

    Utilization of Omics Technology to Analyze Transgenic Plants
    Marisela Rivera-Domínguez and Martín-Ernesto Tiznado-Hernández

    Microalgal Omics and Their Applications
    Shanmugam Hemaiswarya, Rathinam Raja, Ramanujam Ravikumar, Annamalai Yogesh Kumar, and Isabel S. Carvalho

    Plant Metabolomics: Techniques, Applications, Trends, and Challenges
    Shoaib Ahmad

    Nutraceuticals: Applications in Biomedicine
    Vellingiri Vadivel

    Genomic Resources of Agriculturally Important Animals, Insects, and Pests
    Sarika, Anu Sharma, Anil Rai, Mir Asif Iquebal, and Poonam Chilana

    The World of Omics and Applications in Environmental Sciences

    Applications of Molecular Spectroscopy in Environmental and Agricultural Omics
    Daniel Cozzolino

    Metagenomics: Techniques, Applications, and Challenges
    Jyoti Vakhlu and Puja Gupta

    Toxicogenomics in the Assessment of Environmental Pollutants
    Luciana B. Crotti and Luis A. Espinoza

    Omics Approaches in Biofuel Production for a Green Environment
    Atul Grover, Patade Vikas Yadav, Maya Kumari, Sanjay Mohan Gupta, Mohommad Arif, and Zakwan Ahmed

    Environomics: Omics for the Environment
    Dinesh K. Yadav, Neelam Yadav, and Satyendra Mohan Paul Khurana



    Debmalya Barh is the founder and president of the Institute of Integrative Omics and Applied Biotechnology (IIOAB), India, a global platform for multidisciplinary research and advocacy. He is a consultant biotechnologist and has more than 12 years of rich experience in interdisciplinary omics fields. His research areas include integrative omics–based translational researches, target and targeted drug discovery, biomarkers, pharmacogenomics, neutrigenomics, cancer, neuroscience, cardiovascular diseases, infectious and metabolic diseases, and plant, animal, and environmental biotechnology. As an active scientist in the field, he works with nearly 200 researchers from more than 80 institutes across 25 countries. He has edited a number of research reference books in the areas of omics, biomarkers, and other advanced domains in biology. He also serves as an editorial and review board member for several professional international research journals of global repute.

    Vasudeo Zambare is a biochemist. He previously worked at Agharkar Research Institute, India, and the Center for Bioprocessing Research and Development at the South Dakota School of Mines and Technology, USA. His current research concentrates on the use of omics technologies in agriculture, functional food, and environmental sciences. He has published more than 150 peer-reviewed articles and is editor-in-chief, technical editor, associate editor, editorial board member, or advisory member of more than 80 international research journals. He is a fellow member of several international societies, including the Institute of Integrative Omics and Applied Biotechnology (IIOAB).

    Vasco Azevedo is a full professor in molecular biology and genetics at the Federal University of Minas Gerais, Brazil. He is a pioneer scientist in lactic acid bacteria and Corynebacterium pseudotuberculosis and a well-known scientist in bacterial genomics, transcriptomics, proteomics, and metabolomics. His research also involves omics approaches in livestock and agricultural biotechnology in the development of new omics-based vaccines and diagnostics against infectious diseases. He has published 160 research articles and 15 book chapters. He is an associate editor of several journals, including Genetics and Molecular Research, Microbial Cell Factories, and The IIOAB Journal, and an editorial board member of a number of international journals.