622 pages | 11 Color Illus. | 125 B/W Illus.
A reflection of the explosion of research and development in this field, OMICS: Biomedical Perspectives and Applications explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. A select editorial panel of experts discusses their cutting edge omics research and novel technologies, supplying a basic platform of methods and applications and a resource for enhanced cross-pollination in a multiomics approach to future endeavors in the fertile fields of omics research.
After an introduction on the omics universe, the book presents modern omics and its applications in nanotechnology, genomics, proteomics, metagenomics, toxicogenomics, immunomics, nutrigenomics, diabetes, neurology, cardiology, and cancer to name just a few. The book begins with an overview of omics and omic technologies such as cellomics, glycomics, and lipidomics. It also discusses bioinformatics, demonstrating how it can be a tool in omics, and examines the various approaches of omics technology in toxicology research and applications in biomedical sciences.
While there are a long list of omics books available, most focus narrowly on one area. Presenting a wide view of the current status of integrative omics, this resource contains complete coverage of omics in research and therapy, ranging from neuroscience to cardiology. It collates recent developments in the field into a state-of-the-art framework for this discipline.
… this book will be intensively useful to scientists from both academia and industry, teachers and professors, health professionals, and mostly students, who should be encouraged to study and learn from its wisdom.
—From the Foreword by Debasis Bagchi, PhD, MACN, CNS, MAIChE, Department of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy, Houston, Texas
SECTION I: Methodology and Application
Bioinformatics: A Brief Introduction to Changing Trends in Modern Biology, A.A. Singh and P. Somvanshi
Nutrigenomics, M. Verghese and J. Boateng
Omics Approaches in Toxicology Research and Biomedical Applications, N.L. López-Corrales, A. Miyoshi, V. Azevedo, T. Stuztman, and D. Barh
Stem Cells: Basics and Therapeutic Applications, A.K. Arya and K. Tripathi
Emerging Trends of Nanotechnology in Omics-Based Drug Discovery and Development, S. Selvarajan
Magnetic Nanoparticles in Biomedical Applications, R. Zhang and H. Olin
High-Throughput Screening in Medical Diagnosis and Prognosis, M. El Sayed Zaki
High-Throughput Omics: The Application of Automated High-Throughput Methods and Systems for Solutions in Systems Biology, Ü. Kolukisaoglu and K. Thurow
Safety in Diagnostic Imaging Techniques Used in Omics, R. Visaria, S. Prakash, J.T. Vaughan, and D. Shrivastava
SECTION II: Empirical Research
Molecular Genetics of Human Cancers: Modulation of the Tumor Suppressor Function of RB1 Gene Product in Human Vestibular Schwannomas, M.L. Gope, R. Mitra, and R. Gope
Forward Genetics Approach in Genomics: Functional Identifi cation of Unknown Genes, B. Chatterjee
Proteomics of Phagosomal Pathogens: Lessons from Listeria monocytogens and New Tools in Immunology, E. Rodriguez-Del Rio, C. Carranza-Cereceda, L. Fernandez-Prieto, J. Ramós-Vivas, and C. Alvarez-Dominguez
SECTION III: Computational and Systems Biology
In a Quest to Uncover Governing Principles of Cellular Networks: A Systems Biology Perspective, K. Selvarajoo and M. Tsuchiya
Intermolecular Interaction in Biological Systems, Y. Fukunishi
Implanted Brain-Machine Interfaces in Rats: A Modern Application of Neuromics, W. Chen, J. Dai, S. Zhang, X. Zheng, and X. Hu
SECTION IV: Therapeutics
Pharmacogenomics in Development of Disease-Specifi c Therapeutic Strategy, S. Sharma and A. Munshi
Omics Approaches in Cancer Biomarker and Targeted Anticancer Drug Discovery, D. Dhawan and H. Padh
Recent Advances in MicroRNA Expression Profiling Toward a Molecular Anatomy of Tumorigenesis and Applications for Diagnosis, Prognosis, and Therapeutics, H. Ohdaira and K. Yoshida
Marine Metabolomics in Cancer Chemotherapy, D.M. Pereira, G. Correia-da-Silva, P. Valentão, N. Teixeira, and P.B. Andrade
Genome-Wide Association Studies of Type 2 Diabetes: Current Status, Open Challenges, and Future Perspectives, H. Hong, L. Xu, D.L. Mendrick, and W. Tong
Cardiac Channelopathies: Applications of Genomics and Proteomics in Diagnosis and Therapy, C. Viero
Toward an Omic Perspective on Infectious Disease and Its Therapy: Integrating Immunoinformatics, Immunomics, and Vaccinomics, M.N. Davies and D.R. Flower
NeuroAIDS and Omics of HIV Vpr, A. Swarup Verma, U. Pratap Singh, P. Mallick, P. Dhar Dwivedi, and A. Singh
Epigenetics in Neuropsychiatry, T. Archer and K. Blum
Neurogenetics and Nutrigenomics of Reward Deficiency Syndrome, K. Blum
SECTION V: Future Perspective
Future Perspective: Paving a Path to Optimization of Health, D. Barh, M.A. Madigan, and K. Blum