1st Edition

Omics and System Biology Approaches for Delivering Better Cereals

Edited By Dinesh Kumar Saini, Chittaranjan Kole Copyright 2025
    450 Pages 12 Color & 6 B/W Illustrations
    by CRC Press

    Cereals like wheat, rice, maize, and barley have long been the dominant crops in agriculture, providing a significant portion of our food supply. Plant breeders and geneticists have always been interested in improving the yield and quality of cereals. The primary challenges in cereal breeding lie in adapting to climate change and enhancing yield and stress tolerance. In recent years, omics approaches such as genomics, transcriptomics, proteomics, and metabolomics have emerged as valuable tools to understand the genetic and molecular basis of cereal development under optimum and stress conditions. However, studying individual datasets for different cereals has limited our comprehensive understanding of complex traits and biological networks. To overcome this limitation, a systems biology approach is necessary. Systems biology integrates multiple omics data, modeling, and cell activity prediction to gain a holistic understanding of biological processes. By considering the whole system and its interactions, rather than isolated components, researchers can develop predictive models and even re-engineer cells. In the context of cereal improvement, systems biology can play a crucial role in identifying and introducing desirable traits such as yield, quality, and stress tolerance. It may help researchers uncover the molecular underpinnings of complex traits and offer insights for enhancing cereals on a national and international scale.

    The book explores available omics resources, the integration of multi-omics data, and systems biology methods, focusing on their applications in cereals breeding and research. It highlights current and innovative strategies to understand complex traits, improve yield, and enhance resistance to biotic and abiotic stresses. It also addresses the challenges and opportunities associated with modeling multi-omics data and analyzing systems-level information. By leveraging systems biology and integrated omics research, this book aims to redefine the future research agenda for cereal improvement.

    Series Preface


    Omics and System Biology for Developing Climate-ready Cereals: An Overview

    Dinesh Kumar Saini, Sourabh Kumar, Khushi Saini, Simran Goyal

    Databases: A Tool in the Bioinformatics Armory for Cereals Research

    Priyanka Upadhyay, Ronika, Arushi Arora, Shivani Yadav, Sudeshna, Kumar Sanu, Dinesh Kumar Saini, Ashita Bisht

    Genomes, Pangenomes, and Super Pangenomes of Cereals: How to Translate the Generated Information into Genetic Gains

    Ayesha Farooq, Uzair Muhammad Khan, Asad Raiz, Rizwana Maqbool, Zulfqar Ali, Muhammad Sajjad

    QTLomics-based Genetic Dissection of Key Traits in Major Cereals: Challenges and Prospects

    Mukesh Choudhary, Pardeep Kumar, Nitish Ranjan Prakash, Mamta Gupta, Seema Sheoran, Pawan Kumar, Digvijay Singh, Swapnil, BS Jat, Dinesh Kumar Saini

    Potential Applications of CRISPR/Cas9 Mediated Genome-Editing Approaches in Improvements of Cereals

    Neeraj Pal, Jajati Keshari Nayak, Raju Ratan Yadav, Santvana Tyagi, Pooja Joshi, Sundip Kumar

    Advancements in Functional Genomics in Exploring Abiotic Stress Tolerance Mechanisms in Cereals

    Pooja Kumari, Pabitra Joshi, Mohammed Kyum, David Ngure, Lucas Alexandre Batista

    MicroRNA-mediated (Micromics) Approaches to Unravel the Molecular Mechanisms Underlying Stress Tolerance in Cereals

    Priyanka Veerala, Neeraj Pal, Rahul Kumar, Simran Goyal, Simran Kotwal, Mukesh Kumar

    Breeding Climate-smart Cultivars: Can Transcriptomics Enable Strategic Cereal Breeding?

    Palvi Malik, Karminderbir Kaur, Parampreet Kaur, Sushmita Seni, Harmanpreet Kaur

    Proteomics and Cereals Breeding: Current Progress and A Look Ahead to the Next Decade

    Mandeep Singh, Meghna Mandal, Dayanand, Vivek Kumar, Chayanika Lahkar, Harkanwal Pal Singh, Dinesh Kumar Saini

    Plant Metabolomic Profiling to Better Understand Biotic and Abiotic Stress Resistance in Cereals

    Gurjeet Singh, Pradeep Kumar, Parul Mandal, Danishta Aziz, Summira Rafiq, Pawan Saini, Santosh Gudi, Amandeep, Dinesh Kumar Saini

    Epigenomics for Abiotic Stress Tolerance in Cereals

    Tinku Gautam

    Multi-omics Assisted Breeding in Cereals: Applications and Challenges

    Mumtaz Ali Saand, Yaodong Yang

    Utilizing Advanced Omics Approaches for Extricating the Hidden Genetic Variability from Wild Repository for Reviving Genetic Gains in Cereals with Major Emphasis on Rice

    Pawan Saini, Danishta Aziz, Summira Rafiq, Pooja Saini, Neeraja Puthiamadom, Gulab Khan Rohela, Charan Singh, Arya S. Nair, Visakh, R.L., Gayathri G., Shiv Shankar Singh, Gurjeet Singh

    Establishing the Proper Links: Network-based Techniques for Comprehending Gene Functions in Cereals

    Dinesh Kumar Saini


    About the Editors


    Dinesh Kumar Saini, a post-doctoral researcher at Texas Tech University, Texas, USA, specializes in Plant Breeding, Genomics, and Physiology. He recieved presitgious fellowships during his Ph.D. program at Punjab Agricultural University, Punjab, India. He has been recognized with several awards, including Chancellor Silver Medal, University Gold Medal in Crop Improvement, and Vice-Chancellor Gold Medal (twice). He has also contributed to the development of a comprehensive wheat QTL database (http://wheatqtldb.net/) as a core member. He has co-authored over 40 articles in high impact factor journals, 13 book chapters, 8 popular articles, and 25 abstracts, and contributed to two international annual wheat newsletters. He is actively engaged in reviewing the articles for over 20 journals and serving in various editorial roles for some. Additionally, he is a member of several professional societies.

    Chittaranjan Kole is an internationally reputed scientist whose original contributions in the fields of plant genomics and biotechnology has lead to the publication of more than 160 research articles in globally leading journals. He has edited over 190 books for the leading publishers of the world including the Taylor and Francis Group. Earlier he served as Vice-Chancellor of the BC Agricultural University in India. He is also the President of the International Climate-Resilient Crop Genomics Consortium (ICRCGC), International Phytomedomics and Nutriomics Consortium (IPNC) and Genome India International (GII).