1st Edition

Ophthalmological Imaging and Applications

    529 Pages 266 B/W Illustrations
    by CRC Press

    528 Pages 266 B/W Illustrations
    by CRC Press

    Edited by and featuring contributions from world-class researchers, Ophthalmological Imaging and Applications offers a unified work of the latest human eye imaging and modeling techniques that have been proposed and applied to the diagnosis of ophthalmologic problems, including inflammation, cataracts, diabetic retinopathy, and glaucoma. With a focus on theory, basic principles, and results derived from research, the book:

    • Explores various morphological, textural, higher-order spectral, and wavelet transformation techniques used to extract salient features from images of the human eye
    • Examines 2D and 3D finite element and boundary element models of the human eye developed to simulate thermal steady-state conditions
    • Addresses the difficult task of benchmarking the validity of human eye imaging techniques and computer-simulated results with experimental measurements

    Intended to be a companion to Image Analysis and Modeling in Ophthalmology, this volume covers several aspects of multimodal ophthalmological imaging and applications, presenting information in an accessible manner to appeal to a wide audience of students, researchers, and practitioners. Ophthalmological Imaging and Applications considers promising simulations that pave the way for new possibilities in computational methods for eye health care.

    Retinal Vascular Imaging in Clinical Research
    M. Kamran Ikram, Shaun Sim, Yi Ting Ong, Carol Y. Cheung, and Tien Y. Wong

    Detection and Modeling of the Major Temporal Arcade in Retinal Fundus Images
    Faraz Oloumi, Rangaraj M. Rangayyan, and Anna L. Ells

    Application of Higher Order Spectra Cumulants for Diabetic Retinopathy Detection using Digital Fundus Images
    Roshan Joy Martis, Karthikeyan Ganesan, U. Rajendra Acharya, Chua Kuang Chua, Lim Choo Min, E.Y.K. Ng, Augustinus Laude, and Jasjit S. Suri

    Quality Measures for Retinal Images
    S. R. Nirmala, S. Dandapat, and P. K. Bora

    Graph Search Retinal Vessel Tracking
    Enea Poletti and Alfredo Ruggeri

    Fundus Autofluorescence Imaging: Fundamentals and Clinical Relevance
    Yasir J. Sepah, Abeer Akhtar, Yammama Hafeez, Humzah Nasir, Brian Perez, Narissa Mawji, Muhammad Ali Sadiq, Diana J. Dean, Daniel Ferraz, and Quan Dong Nguyen

    The Needs/Requirements and Design of Imaging and Image Processing Methods for Ophthalmology in the Indian Context
    Sudipta Mukhopadhyay, Amod Gupta, and Reema Bansal

    The Application of Ocular Fundus Photography and Angiography
    C. Chee, P. Santiago, G. Lingam, M. Singh, T. Naing, E. Mangunkusumo, and M. Nasir

    Optic Nerve Analysis and Imaging in Relation to Glaucoma
    Seng Chee Loon, Victor Koh, and Rosalynn Grace Siantar

    Imaging of the Eye after Glaucoma Surgery
    Mandeep S. Singh, Maria Cecilia D. Aquino, and Paul T. K. Chew

    Confocal Microscopy of Cornea
    Manotosh Ray, Anna W.T. Tan, and Dawn K.A. Lim

    Corneal Topography and Tomography: The Orbscan II
    Anna W.T. Tan, Manotosh Ray, and Dawn K.A. Lim

    Automatic Analysis of Scanning Laser Ophthalmoscope Sequences for Arteriovenous Passage Time Measurement
    Castor Mariño, Marcos Ortega, Jorge Novo, Beatriz Remeseiro, Alba Fernandez, and Francisco Gomez-Ulla

    Optical Coherence Tomography
    Mohamed A. Ibrahim, Yasir J. Sepah, Millena G. Bittencourt, Hongting Liu, Mostafa Hanout, Daniel Ferraz, Diana V. Do, and Quan Dong Nguyen

    The Role of Optical Coherence Tomography on Imaging of the Ocular Surface
    Tin Aung Tun, Sze-Yee Lee, Rachel Nge, and Louis Tong

    Anterior Segment Imaging of Anterior Segment Optical Coherence Tomography (ASOCT)
    Zheng Ce and Paul Chew Tec Kuan

    Cyst Detection in OCT Images for Pathology Characterization
    Ana Gonzalez, Beatriz Remeseiro, Marcos Ortega, Manuel G. Penedo, and Pablo Charlon

    Scanning Laser Ophthalmoscope Fundus Perimetry: The Microperimetry
    Millena G. Bittencourt, Daniel Ferraz, Hongting Liu, Mostafa Hanout, Yasir J. Sepah, Diana V. Do, and Quan Dong Nguyen

    In Vivo Confocal Microscopy: Imaging of the Ocular Surface
    Sze-Yee Lee, Shakil Rehman, and Louis Tong

    Biomechanical Modeling of Blood Vessels for Interpretation of Tortuosity Estimates
    Martynas Patašius, Vaidotas Marozas, Darius Jegelevičius, Arūnas Lukoševičius, Irmantas Kupčiūnas, and Audris Kopustinskas

    Hybrid Finite Element Simulation for Bioheat Transfer in Human Eye
    Hui Wang, Qing Hua Qin, and Ming-Yue Han

    Effects of Electromagnetic Fields on Specific Absorption Rate and Heat Transfer in the Human Eye
    Teerapot Wessapan and Phadungsak Rattanadecho

    Dry-Eye Characterization by Analysis of Tear Film Images
    Beatriz Remeseiro, Manuel G. Penedo, Carlos Garcia-Resua, Eva Yebra-Pimentel, and Antonio Mosquera

    Thermography and the Eye: A Look at Ocular Surface Temperature
    Dawn K.A. Lim, Thet Naing, and Caroline Chee


    E. Y. K. Ng received his Ph.D from Cambridge University, UK and is an associate professor at Nanyang Technological University, Singapore. He serves as editor for six international journals and as editor-in chief for two SCIE-indexed journals. He is an invited speaker at many international scientific conferences and workshops. His research interests are in thermal imaging, biomedical engineering, breast cancer detection, computational fluid dynamics, and heat transfer.

    U. Rajendra Acharya holds a Ph.D from National Institute of Technology Karnataka, Surathkal, India and a D.Eng from Chiba University, Japan. His interests are in biomedical signal processing, bio-imaging, data mining, visualization, and biophysics for better healthcare design, delivery, and therapy. He has worked on various funded projects with grants worth over 1.5 million SGD. He holds faculty positions with Ngee Ann Polytechnic, Singapore; SIM University, Singapore; Singapore Institute of Technology-University of Glasgow Degree Programme; and Manipal Institute of Technology, India. Widely published, he often acts as a guest editor and serves on the editorial board of many journals.

    Rangaraj M. Rangayyan is a professor at the University of Calgary, Alberta, Canada. He is a pioneer in the field of computer-aided diagnosis and a fellow of the Institute of Electrical and Electronics Engineers (IEEE), American Institute for Medical and Biological Engineering, Society of Photo-optical Instrumentation Engineers, Engineering Institute of Canada, Society for Imaging Informatics in Medicine, Canadian Medical and Biological Engineering Society, and Canadian Academy of Engineering. His areas of research are digital signal and image processing, biomedical signal and image analysis, and medical imaging. He has been recognized with the 2013 IEEE Canada Outstanding Engineer Medal and the IEEE Third Millennium Medal (2000).

    Jasjit S. Suri holds a MS from University of Illinois, Chicago; Ph.D from University of Washington, Seattle; and MBA from Weatherhead School of Management, Case Western Reserve University, Cleveland, Ohio. A committee member of several journals and companies, he has spent over 25 years in biomedical engineering/sciences, written over 350 peer-reviewed publications, been crowned with the President’s Gold Medal, and been named fellow of the American Institute of Medical and Biological Engineering (AIMBE) by the National Academy of Sciences, Washington, District of Columbia. He also served as chairman of IEEE Denver and received over 50 awards during his career.