Organ Specific Drug Delivery and Targeting to the Lungs provides up to date information on the multidisciplinary field of particle engineering and drug delivery to the lungs, including advancements of nanotechnology. The text presents a unique, pragmatic focus with case studies, that help translate scientific understanding to practical implementation. In addition to highlighting the successful case studies, it also offers practical advice on watchouts, limitations, and ‘bookend’ boundaries involved in the stages of testing and development.
Additional Features Include:
- Provides an account of particle engineering, discovery, biology, development, and delivery in relation with the advancements of nanotechnology, unlike any previous book.
- Brings together the leading experts and researchers in the field to critically assess and discuss various topics influencing drug delivery.
- Highlights the interplay of different scientific disciplines and the balance of requirements that are critical to molecule and product design.
With the strategic focus on what matters during new product development, this book provides a guide to understanding and navigating new drug discovery and development for lung targets.
Estimating Clinically Relevant Measures of Inhaled Pharmaceutical Aerosol Performance with Advanced In Vitro and In Silico Methods
In Vitro Assessment of Drug Release, Dissolution, and Absorption in the Lung
Lung-on-a-Chip and Lung Organoid Models
Interaction between Inhalable Nanomedicines and Pulmonary Surfactant
Particle engineering for pulmonary drug delivery
Particle Architectonics for Pulmonary Drug Delivery
Engineered Particles for Aerosolisation and Lung Deposition
Recent advances in inhalable nanomedicine for lung cancer therapy
Thin-Film Freeze-Drying Process for Versatile Particles for Inhalation Drug Delivery
Nanoparticles as specific drug carriers
Surface modification of micronized drug particles for aerosolization
Spray Dried Particles for Inhalation
Inhalation Aerosol Phospholipid Particles for Targeted Lung Delivery
Protein and Peptide Delivery to the Lung via Inhalation
Exosomes Based Drug Delivery for Lung Cancer Treatment