1st Edition
Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome
Edited By Helmut Sies
Copyright 2008
344 Pages
by
CRC Press
344 Pages
by
CRC Press
344 Pages
by
CRC Press
Also available as eBook on:
Characterized by obesity, insulin resistance, dyslipidemia, and hypertension, metabolic syndrome is associated with the risks of type 2 diabetes mellitus and cardiovascular disease. Obesity, which increases the incidence of atherosclerotic cardiovascular disease and subsequently leads to increased stress and inflammation, appears to play a central role in the progression of the syndrome. Evidence... Read more
The Metabolic Syndrome Defined. The Metabolic Syndrome: The Question of Balance between the Pro-Inflammatory Effect of Macronutrients and the Anti-Inflammatory Effect of Insulin. The Role of Oxidative Stress in Diseases Associated with Overweight and Obesity. Metabolic Syndrome Due to Early Life Nutritional Modifications. Oxidative Stress and Antioxidants in Perinatal Period. Maternal Obesity, Glucose Intolerance, and Inflammation in Pregnancy. Obesity, Nutrigenomics, Metabolic Syndrome, and Type 2 Diabetes. Post-Prandial Endothelial Dysfunction, Oxidative Stress, and Inflammation in Type 2 Diabetes. Obesity and Inflammation: Implications for Atherosclerosis. Oligomeric Composition of Adiponectin and Obesity. Insulin-Stimulated Reactive Oxygen Species and Insulin Signal Transduction. Intracellular Signaling Pathways and Perixosome Proliferator-Activated Receptors in Vascular Health in Hypertension and in Diabetes. Role of Uncoupling Protein 2 in Pancreatic ß-Cell Function: Secretion and Survival. Nutritional Modulation of Inflammation in Metabolic Syndrome. Dietary Fatty Acids and Metabolic Syndrome. Lipid-Induced Death of Macrophages: Implication for Destabilization of Atherosclerotic Plaques. a-Lipoic Acid Prevents Diabetes Mellitus and Endothelial Dysfunction in Diabetes-Prone Obese Rats. Lipoic Acid Blocks Obesity through Reduced Food Intake, Enhanced Energy Expenditure, and Inhibited Adipocyte Differentiation. Effects of Conjugated Linoleic Acid and Lipoic Acid on Insulin Action in Insulin-Resistant Obese Zucker Rats. Trivalent Chromium Supplementation Inhibits Oxidative Stress, Protein Glycosylation, and Vascular Inflammation in High Glucose-Exposed Human Erythrocytes and Monocytes. Index.
Biography
Lester Packer, Helmut Sies
