This volume gives special reference to papillomaviruses in benign precursor lesions related to genital tumors, plus it provides a basis for a more reproducible evaluation of the pathology of papillomavirus-induced lesions. It deals with the molecular biology of papillomaviruses as it relates to our understanding of viral cell transformation and malignant conversion. Written in a comprehensive, easy-to-read format, this book covers points of medical interest such as diagnosis, therapy, and prospects for vaccination. This fascinating text provides current, state-of-the-art practices for immediate and future medical research. Virologists, microbiologists, and cancer researchers will find this work interesting and resourceful.
General Introduction to Papillomaviruses. Association of Human Papillomavirus with Benign, Premalignant and Malignant Anogenital Lesions. Human Papillomaviruses in Skin Carcinomas. Papillomaviruses and Human Cancer. Bovine Papillomavirus Type 1 Transcription. The Genetics of Bovine Papillomavirus Type 1. Cell Transformation by Human Papillomaviruses. State of Viral DNA and Gene Expression in Benign vs. Malignant Tumors. Papillomavirus Genomes: Sequence Analysis Related to Functional Aspects. Therapy of Papillomavirus Induced Lesions. Detection of Human Papillomavirus Infection and Prospects for Diagnostics. Immunobiology of Papillomaviruses and Prospects for Vaccination. Index.