The first in a new series created to acknowledge the explosion of knowledge in fields related to infectious disesases and clinical microbiology. Thirteen contributions focus on organisms which are of major medical importance in this country or which have contributed to an understanding of pathology.
Table of Contents
Series Introduction -- Preface -- Contributors -- 1. The Compromised Host: AIDS and Other Diseases /Henry Masur -- I. Introduction -- II. Host Defense Mechanisms -- III. Etiology and Pathogenesis of Infection -- IV. Protozoa and Helminths in Compromised Patients -- V. Special Patient Populations -- VI. Conclusion -- References -- 2. Host Defenses Against Prototypical Intracellular Protozoans, the Leishmania /Richard D. Pearson and Mary E. Wilson -- I. Introduction -- II. The Parasite -- III. Genetic Determinants of Resistance -- IV. Early Events -- V. Later Events -- VI. Conclusion -- References -- 3. Pneumocystis carinii /Peter D. Walzer, C Kurtis, Kim, and Melanie T. Cushion -- I. Introduction -- II. The Organism -- III. The Host -- IV. The Disease -- References -- 4. Toxoplasma gondii /Benjamin J. Luft -- I. Introduction -- II. Epidemiology -- III. Life Cycle -- VI. Growth and Metabolism -- V. Antigenic Structure -- VI. Evasion of Host Defense -- VII. Development of Protective Immunity -- VIII. Genetic Variability in Host Resistance -- IX. Host Factors Associated with Disseminated Toxoplasmosis -- X. Pathogenesis of Toxoplasmosis -- XI. Pathology -- XII. Clinical Manifestations -- XIII. Diagnosis -- XIV. Treatment -- xv. Prevention -- References -- 5. Oyptosporidium spp. /William L. Current -- I. Introduction -- II. The Organism -- III. The Host -- IV. The Disease -- References -- 6. Giardia lamblia /Phillip D. Smith -- I. Introduction -- II. The Organism -- III. The Host -- IV. The Disease -- V. Conclusion -- References -- 7. Entamoeba histolytica /William A. Petri, Jr., and Jonathan I. Ravdin -- I. Introduction -- II. The Organism -- III. The Host -- IV. The Disease -- References -- 8. The Hoist Immune Response Against Parasitic Helminth Infection /Thomas B. Nutman -- I. Introduction -- II. The Parasites -- III. Genetic and Environmental Determinants of Susceptibility to Infection -- IV. Evasion of the Immune Response by the Parasites -- V. Immunological Consequences of Parasitic Infection -- VI. Unique Features of the Immune Responses to Helminth Parasites -- VII. Effector Mechanisms Mediating Host Immunity to Helminth -- Parasites -- References -- 9. Strongyloidiasis /Robert M. Genta and Peter D. Walzer -- I. Introduction -- II. Taxonomy -- III. Llfe Cycle -- IV. Morphology and Physiology -- V. Virulence and Antigenicity -- VI. Epidemiology and Transmission -- VII. Pathology and Pathogenesis -- VIII. Host Responses -- IX. Animals Models -- X. Clinical Manifestations -- XI. Diagnosis -- XII. Treatment -- XIII. Prevention -- References -- Index.
PETER D. WALZER is Chief of the Division of Infectious Diseases at the Cincinnati Veterans Administration Center, and Professor of Medicine as well as of Pathology and Laboratory Medicine at the University of Cincinnati College of Medicine in Cincinnati, Ohio. An authority on Pneumocystis carinii pneumonia, he has published nearly 100 articles, book chapters, and proceedings papers, and he has presented numerous papers at conferences throughout the U.S. He is a Fellow of the American College of Physicians and Infectious Disease Society of America, and he is a member of the American Society for Microbiology, American Society of Tropical Medicine and Hygiene, American Society of Parasitologists, American Thoracic Society, American Association of Immunologists, and others. Dr. Walzer received the B.S. degree (1964) from Boston College and M.D. degree (1968) from Albany Medical College in Albany, New York. ROBERT M. GENT A is Associate Professor of Pathology and Laboratory Medicine at the University of Cincinnati College of Medicine and a Staff Pathologist at the Veterans Administration Medical Center in Cincinnati, Ohio. He is the author or coauthor of some 40 articles and book chapters, many of them concerning his research specialty in Strongyloides stercoralis. Among the professional societies he belongs to are the College of American Pathologists, American Public Health Association, American Society of Tropical Medicine and Hygiene, American Society of Parasitologists, and New York Academy of Sciences. Dr. Genta received the M.D. degree (1971) from the University of Turin Medical School in Italy and a diploma (1977) from the University of Liverpool's Liverpool School of Tropical Medicine in the U.K.