An up-to-the-minute reference guide for health professionals confronting pulmonary disorders in children, Pediatric Asthma offers the latest findings on this classification-defying disease and related conditions. Written by more than 20 international experts in the field, the book focuses on drug administration-issues of compliance, aerosol delivery, and pharmacokinetic differences among children-with a view toward developing new and more efficacious therapies.
    Provides cutting-edge analysis for more effective diagnosis of children with asthma and improved monitoring and treatment for chronic patients!
    With a firm theoretical grounding and reflecting the state of the art in pharmacological research and development, Pediatric Asthma

  • reviews the prevalence, causes, and demographics of childhood asthma worldwide
  • explores determinants of the disorder in various populations-gender, age and severity of onset, atopic status, family history, and smoking
  • elucidates physiological factors such as airway remodeling, airway hyperresponsiveness, and persistent inflammation
  • describes in vivo and in vitro testing for asthma-associated allergy and the pros and cons of allergen immunotherapy
  • delineates the dynamics of the lung in terms of phenomena such as peak expiratory flow (PEF), forced vital capacity (FVC), and bronchial hyperresponsiveness (BHR)
  • highlights the importance of patient education and self-management
  • investigates the role that developmental psychopathologies and neurobehavioral dysfunctions may play in pediatric asthma
  • discusses inflammatory mediators such as cytokines, chemokines, leukotrienes, and prostaglandins
  • evaluates intravenous and inhaled 2 agonists for the bronchodilating treatment of acute severe asthma
  • and more!
    Featuring over 2100 references, more than 60 user-friendly tables, and a handy Appendix on clinical monitoring of childhood asthma and recommended drug dosages for its treatment, Pediatric Asthma is an indispensable resource for pediatricians, pediatric pulmonologists, and pediatric pharmacists; clinical allergists and immunologists; general and family practitioners; and graduate and medical school students in these disciplines.
  • Epidemiology of Childhood Asthma, Erika von Mutius and Fernando D. Martinez
    The Natural History of Asthma, Iqbal H. Ahmed and Jonathan M. Samet
    Pathophysiology, Mario Castro, Thomas F. Smith, and Robert C. Strunk
    The Role of Allergy, Harold S. Nelson
    Pulmonary Function Testing, Howard Eigen
    Chronic Therapy Overview, Gail G. Shapir
    Patient Education in Pediatric Asthma, Jean E. Hanson
    Psychology of Pediatric Asthma, Robert D. Annett and Bruce G. Bender
    The Management of Acute Severe Asthma, H. William Kelly and Shirley Murphy
    Intensive Care Unit Management, Robert Katz
    2 Agonists, John W. Jenne and H. William Kelly
    Glucocorticoids, Alan K. Kamada and Stanley J. Szefler
    Theophylline, Kathryn Blake
    Cromolyn, Nedocromil, Leukotriene Modifiers, and Alternative Anti-Inflammatory Agents in the Treatment of Pediatric Asthma, Christine A. Sorkness
    Aerosol Delivery, H. William Kelly
    Appendix: Available Preparations and Usual Pediatric Dosing Range, Patricia Marshik, H. William Kelly, Alan K. Kamada

    Biography

    Shirley J. Murphy, H. William Kelly

    "
    ….this is a well written, easy to understand, timely, and comprehensive book that covers all aspects of pediatric asthma, from epidemiology to treatment to education….it is the most complete and up-to-date reference in pediatric asthma published to date.
    "-Respiratory Care

    "….Pediatric Asthma is well written and includes current information….
    …recommend[ed]…because of the magnitude of information presented. It is a valuable resource for those in the pharmaceutical field and students or practitioners who are learning about asthma. The…price is…justified by the volume of information the book contains.
    "- The Annals of Pharmacology