Pediatric Radiotherapy Planning and Treatment

Section 1: Pediatric Cancers and Challenges for Radiotherapy
Overview of Childhood Cancer: Incidence, Survival, and Late Effects
Challenges of Treating Children with Radiation Therapy
Overview
Treatment Planning Considerations
Secondary Malignancies
Appendix
Section 2: Guide to Treatment Planning and Dose Delivery
Leukemia
Clinical Overview
Total Body Irradiation (TBI) as Preparation for Bone Marrow Transplant
Early Animal and In Vitro Radiobiological Data
Clinical Basis for TBI Prescription
TBI Delivery Method Evolution
Conventional TBI Treatment Methods
Conventional TBI Commissioning and Dosimetry Requirements
Treatment Planning
Organ-at-Risk Doses and Late Effects
Tumors of the Central Nervous System
Clinical Overview
Target Volume Definition
Treatment Strategies
Organ-at-Risk Doses and Late Effects
Appendix
Hodgkin Lymphoma
Clinical Overview
General Treatment Planning Guidelines
Three-Dimensional Conformal Radiation Therapy (3DCRT) and Intensity-Modulated Radiation Therapy (IMRT) for Hodgkin Lymphoma (HL)
Organ-at-Risk Doses and Late Effects
Neuroblastoma
Clinical Overview
Target Volume Definition
Treatment Planning Techniques and Dosimetry
Organ-at-Risk Doses and Late Effects
Wilms’ Tumor
Clinical Overview
Field Design
Intensity-Modulated Radiation Therapy (IMRT) Treatment Planning
Proton Therapy
Organ-at-Risk Doses and Late Effects
Soft Tissue Tumors (Rhabdomyosarcoma and Other Soft Tissue Sarcomas)
Clinical Overview
External Beam Treatment Planning
Brachytherapy and Intraoperative Electron Beam (IORT)
Proton Therapy
Organ-at-Risk Doses and Late Effects
Bone Sarcomas (Osteosarcoma and Ewing’s Sarcoma)
Clinical Overview
Treatment Planning
Late Effects
Retinoblastoma
Clinical Overview
Treatment Planning
Treatment Techniques
Organ-at-Risk Doses and Late Effects
Index
References appear at the end of each chapter.

Biography

Arthur J. Olch is a professor of clinical pediatrics and radiation oncology in the Keck School of Medicine at the University of Southern California. He is also chief of physics for the Children’s Hospital of Los Angeles Radiation Oncology Program, one of only a few radiotherapy centers in the United States that treats children exclusively. Dr. Olch earned a PhD in medical physics from the University of Los Angeles. A Fellow of the American Association of Physicists in Medicine (AAPM), Dr. Olch has authored or coauthored more than 40 journal articles and book chapters.

"This is a very well-written and -organized book covering the planning and delivery aspects unique to pediatric radiotherapy. The author is a respected and well-known medical physicist with extensive pediatric radiotherapy experience. … a very useful book for any clinical physicist treating pediatric cases and seeking contextual and historical perspective. … a great reference for medical physicists who may not see many pediatric cases and can look to this text as a one-stop shop for not only a comprehensive overview, but detailed explanation for specific pediatric disease sites. Overall, it is a great addition to the reference library of any radiation therapy physicist."
—Medical Physics, April 2014