Pediatric Tumors: Immunological and Molecular Markers, 1st Edition (Hardback) book cover

Pediatric Tumors

Immunological and Molecular Markers, 1st Edition

By John T. Kemshead

CRC Press

200 pages

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Hardback: 9780849367526
pub: 1989-05-31
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Description

This monograph explains the considerable impact that monoclonal antibodies and molecular probes have had on the diagnosis of tumor types and sub-types. It explains how radiolabelled monoclonal antibodies have also been used as imaging agents to try to improve the oncologist's ability to define residual tumor deposits after combination chemo/radiotherapy. Finally, the childhood malignancies that still have a poor prognosis are presented, and new novel ways of therapy are explained.

Reviews

…"up-to-date, comprehensive, and thought-provoking."

-Acta Oncologica

Table of Contents

Pathology and Epidemiology. Monoclonal Antibodies Used for Diagnosis of Small Round Cell Tumors of Childhood. An Immunohistological Approach to Differential Diagnosis of Childhood Brain Tumors. Sereological Studies Using Monoclonal and Polyclonal Antibodies - Their Diagnostic and Prognostic Usefulness. Ganglioside GD2 Specific Antibodies in the Diagnosis and Therapy of Human Neuroblastoma. The Development of Targeted Radiotherapy for Treatment of Small Round Cell Tumors of Childhood. Monoclonal Antibodies as Agents to Purge Tumor Cells from Bone Marrow: Laboratory and Clinical Experiences. Molecular Approaches Toward Isolation of Pediatric Cancer Predisposition Genes. Gene Rearrangement in Leukemias and Lymphomas. The N-Myc Oncogene in Pediatric Tumors: Diagnostic, Prognostic, and Biological Aspects. Index

Subject Categories

BISAC Subject Codes/Headings:
MED062000
MEDICAL / Oncology
MED067000
MEDICAL / Pathology
MED069000
MEDICAL / Pediatrics