2nd Edition
Phage Display In Biotechnology and Drug Discovery
Filamentous Bacteriophage Structure and Biology
Diane J. Rodi, Suneeta Mandava, and Lee Makowski
Vectors and Modes of Display
Valery A. Petrenko and George P. Smith
Methods for the Construction of Phage-Displayed Libraries
Frederic A. Fellouse and Gabor Pal
Selection and Screening Strategies
Mark S. Dennis
Leveraging Synthetic Phage-Antibody Libraries for Panning on the Mammalian Cell Surface
Jelena Tomic, Megan McLaughlin, Traver Hart, Sachdev Sidhu, and Jason Moffat
Phage Libraries for Developing Antibody-Targeted Diagnostics and Vaccines
Nienke E. van Houten and Jamie K. Scott
Exploring Protein-Protein Interactions Using Peptide Libraries Displayed on Phage
Kurt Deshayes
Substrate Phage Display
Shuichi Ohkubo
Mapping Intracellular Protein Networks
Malgorzata E. Kokoszka, Zhaozhong Han, Ece Karatan, and Brian K. Kay
High-Throughput and High-Content Screening Using Peptides
Robert O. Carlson, Robin Hyde-Deruyscher, and Paul T. Hamilton
Engineering Protein Folding and Stability
Mihriban Tuna and Derek N. Woolfson
Identification of Natural Protein-Protein Interactions with cDNA Libraries
Reto Crameri, Claudio Rhyner, Michael Weichel, Sabine Fluckiger, and Zoltan Konthur
Mapping Protein Functional Epitopes
Sara K. Avrantinis and Gregory A. Weiss
Selections for Enzymatic Catalysts
Julian Bertschinger, Christian Heinis, and Dario Neri
Antibody Humanization and Affinity Maturation Using Phage Display
Jonathan S. Marvin and Henry B. Lowman
Antibody Libraries from Immunized Repertoires
Jody D. Berry and Mikhail Popkov
Naive Antibody Libraries from Natural Repertoires
Claire L. Dobson, Ralph R. Minter, and Celia P. Hart-Shorrock
Synthetic Antibody Libraries
Frederic A. Fellouse and Sachdev S. Sidhu
Engineering Antibody Fragments for Intracellular Applications
Jianghai Liu and C. Ronald Geyer
Biography
Edited by
Sachdev S. Sidhu, PhD, professor, Department of Molecular Genetics, University of Toronto, Ontario, Canada
C. Ronald Geyer, PhD, professor, Department of Pathology, University of Saskatchewan, Canada
“… The book covers broadly all aspects of phage-display technology and will be highly appreciated by those working with this technique and interested in applications. … The book is a clear invitation to use the phage-display technique both in biotechnology and drug discovery; … this is a very comprehensive book demonstrating the versatility and the value of phage display in many applications. It is clearly written giving an interesting historical background to many presently used variations on the phage-display technique.”
—Wim Quax, Rijksuniversiteit Groningen, The Netherlands, in ChemBioChem, Vol. 7, No. 699 - 703
