1st Edition

Pharmaceutical Perspectives of Nucleic Acid-Based Therapy

ISBN 9780367454883
Published December 18, 2020 by CRC Press
560 Pages

USD $69.95

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Book Description

Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications. Internationally acclaimed scientists discuss the potential use of lipids, peptides and polymers for the in vivo delivery of nucleic acids, the genesis of structure-synthesis-function interrelationships and the evolutionary approaches of these gene carriers. The book also addresses the influence of a viable gene expression system on disease by controlling gene regulation, transcription, translation and replication.

Table of Contents

Gene Expression. Modulation of Gene Expression. Biophysical Aspects of Nucleic Acids and Carriers. Intracellular Trafficking. Nucleic Acid Delivery Systems. Biodistribution and Pharmacokinetics. Clinical Applications of Gene Therapy.

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Ram I. Mahato