Pharmacokinetics for the Pharmaceutical Scientist: 1st Edition (Paperback) book cover

Pharmacokinetics for the Pharmaceutical Scientist

1st Edition

By John G. Wagner

CRC Press

336 pages

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Description

Major presentation of pharmacokinetics by a leading international expert. Methods for: estimating drug disposition parameters from data obtained after intravascular or extravascular drug administration, estimating rate and extent of drug bioavailability, and comparing rate and extent of drug availability following administration of several different dosage forms of a drug.

Table of Contents

Simple Linear Models More Complicated Linear Models Complicated Linear Models Linear Multicompartment Disposition Parameters from Extravascular Downslope C,T Data Noncompartmental and System Analysis Linear Multiple Dose Equations Simple Nonlinear Models More Complicated Nonlinear Models Urinary Excretion Absorption Analysis and Bioavailability Physiological Pharmacokinetics Relationship between Physiologically Based Flow Models and Usual Compartment Models Protein Binding Pharmacokinetic Pharmacodynamic Modelling Metabolic Kinetics Laplace Derivation of Linear Pharmacokinetic Equations Measures of Fit Appendix Index 175 Figures and Schematics, 51 Tables, 134 References

About the Author

Wagner, John G.

Subject Categories

BISAC Subject Codes/Headings:
MED071000
MEDICAL / Pharmacology
SCI013000
SCIENCE / Chemistry / General