Completely revised and updated, this is the seventh edition of Levine's classic pharmacology textbook. Known for it's thorough coverage and intelligent organization, the book covers the basic principles of pharmacological interactions on the human body in a way that is useful for both undergraduate and graduate students. Beginning with historical perspectives, nomenclature and definitions, the topics broaden to include sites and mechanisms of drug actions and travel to sites of action, as well as termination and elimination. The book also includes drug response and time-response relationships, response variability, drug toxicity, drug abuse, drug dependence, and more.
Table of Contents
The Heritage of Pharmacology. The Scope of Pharmacology. How Drugs Act on the Living Organism. How Drugs Reach Their Site of Action I. General Principles of Passage of Drugs Across Biological Barriers. How Drugs Reach Their Site of Action II. Absorption. How Drugs Reach Their Site of Action III. Distribution. How the Actions of Drugs Are Terminated I. Excretion. How Actions of Drugs Are Terminated II. Biotransformation. General Principles of the Quantitative Aspects of Drug Action I. Dose-Response Relationship. General Principles of the Quantitative Aspects of Drug Action II. Time-Response Relationships. Factors Modifying the Effect of Drugs in Individuals II. Variability In Response Attributable to the Conditions of Administration. Drug Toxicity. How Drugs Alter Physiologic Function: A Recapitulation. The Pharmacological Aspects of Drug Abuse and Dependence. The Development and Evaluation of New Drugs. Glossary.