Pharmacotherapies for the Treatment of Opioid Dependence: Efficacy, Cost-Effectiveness and Implementation Guidelines, 1st Edition (Paperback) book cover

Pharmacotherapies for the Treatment of Opioid Dependence

Efficacy, Cost-Effectiveness and Implementation Guidelines, 1st Edition

Edited by Richard P. Mattick, Robert Ali, Nicholas Lintzeris

CRC Press

506 pages

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pub: 2009-03-25
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Description

The most comprehensive text of its kind, this book addresses both the management of opioid withdrawal and opioid maintenance therapy, and combines up-to-date reviews of the scientific literature with evidence-based clinical guidelines for all of the relevant pharmacotherapies.

A unique work, Pharmacotherapies for the Treatment of Opioid Dependence presents:

· detailed information on the cost-effectiveness of the various types of opioid treatment

· the range of pharmacotherapies used for the management of opioid dependence

· the state of knowledge from the international research literature on the value and relative efficacy of the various pharmacological approaches.

This includes pharmacotherapies used in the management of withdrawal from opioids such as clonidine, lofexidine, methadone, buprenorphine and naltrexone and also symptomatic medications. It also includes different forms of maintenance therapy using opioid agonists such as methadone, LAAM, buprenorphine, slow-release oral morphine and diamorphine, and opioid antagonists such as naltrexone.

This text should appeal to researchers, to identify gaps in the research literature and provide a basis for determining appropriate research directions, to clinicians by providing clinical with clinical guidelines and information concerning the empirical basis for the treatments, and to policy makers in assisting them to make decisions about the various treatments from a public health perspective, taking into account the relative cost and effectiveness of the interventions.

Table of Contents

Opioid dependence and management

Pharmacology of opioid agonists and antagonists

Services for heroin withdrawal: A review

Methadone maintenance treatment

LAAM in the treatment of opioid dependence: A systematic review

The place of buprenorphine in the management of opioid dependence

Treating heroin dependence with diamorphine (pharmaceutical heroin)

Naltrexone maintenance treatment

Pharmacotherapies and pregnancy

Politics, practice, and research into treatment of heroin addiction

Clinical guidelines and procedures for the use of methadone in the maintenance treatment of opioid dependence

National clinical guidelines and procedures for the use of buprenorphine in the treatment of heroin dependence

Clinical guidelines and procedures for the use of naltrexone in the management of opioid dependence

Choosing treatments: The role of economics in informing future decisions

Subject Categories

BISAC Subject Codes/Headings:
MED071000
MEDICAL / Pharmacology
MED105000
MEDICAL / Psychiatry / General