This book is the first to be published as a single source reference on phosphatidylcholine metabolism. It provides a cogent and timely summary of research in this topic.
Beginning with a chapter by Eugene Kennedy providing an historical perspective; the book proceeds to describe the latest developments in enzymes involved in phosphatidylcholine biosynthesis. Biological chemists, students, and investigators in the field of lipid metabolism will find this book of great benefit in their research.
Discovery of the Pathways for the Biosynthesis of Phosphatidylcholine. Choline Transport and Choline Kinase. CTP: Cholinephosphate Cytidylyltransferase. Cholinephosphotransferase. Phospholipase D and the Base Exchange Enzyme. Phosphatidylcholine Biosynthesis from Lysophosphatidylcholine. Phosphatidylethanolamine N-Methyltransferase. The Role of Phospholipases in Phosphatidylcholine Catabolism. Metabolism of the Ether Analogs of Phosphatidylcholine, Including Platelet Activating Factor. Phosphatidylcholine Metabolism in Saccharomyces cerevisiae. Sphingomyelin Biosyntheses and Catabolism. Metabolism of Phosphatidylcholine in Lung. Regulatory and Functional Aspects of Phosphatidylcholine Metabolism. Index.