Throughout human history, we have long encountered the combination of promise, risk, and uncertainty that accompanies emerging technologies. Nanotechnology is a recent example of an emerging technology that promises to drastically improve existing products as well as allow for creative development of new goods and services. This new technology also has its potential downsides. Industry, academia, and regulatory agencies are all working overtime to assess risks accurately while keeping up with the pace of development.
Subtle changes in the physicochemical properties of engineered nanomaterials (ENMs) can influence their toxicity and behavior in the environment and so can be used to help control potential ENM risks. This book attempts to encompass the state of the science regarding physicochemical characterization of ENMs. It illuminates the effort to understand these properties and how they may be used to ensure safe ENM deployment in existing or future materials and products.
Table of Contents
How Physical and Chemical Information Predicts the Action of Molecules: A Historical Overview
Physicochemical Characterization: From Molecules to Particles
Common Physicochemical Properties
Physicochemical Properties of Engineered Nanomaterials and Their Importance in Assessing Relevant Metrics of Inhalation Exposures in Occupational Settings
Physicochemical Properties and Their Importance in the Environment: Current Trends in Nanomaterial Exposure
Categorizing Nanomaterials for Health and Environmental Risk Assessment
The Regulatory Use of Physicochemical Properties by Environmental Agencies
Physicochemical Properties of Nanomaterials Relevant to Medical Products
Richard C. Pleus is the founder of the internationally known toxicology consulting organization Intertox, Inc. He is a leader in nanotechnology safety and has been an advisor to the U.S.−Russia Bilateral Presidential Commission on science and technology; the International Organization for Standardization, Switzerland; and the National Institute for Occupational Health and Safety, USA.
Vladimir Murashov is a globally recognized expert in safety of nanotechnology and other emerging technologies. He serves as a senior scientist in the Office of the Director of the National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, USA. He also leads nanotechnology safety groups in the International Organization for Standardization, Organization for Economic Cooperation and Development, and World Health Organization.