Phytochemicals : Mechanisms of Action book cover
1st Edition

Mechanisms of Action

ISBN 9780849316722
Published December 15, 2003 by CRC Press
224 Pages 43 B/W Illustrations

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Book Description

Phytochemicals: Mechanisms of Action is the latest volume in a highly regarded series that addresses the roles of phytochemicals in disease prevention and health promotion. The text, an ideal tool for scientists and researchers in the fields of functional foods and nutraceuticals, links diets rich in plant-derived compounds, such as fruit, vegetables and whole grains, with decreased risk of chronic degenerative diseases.

Chapters highlight recent developments in three areas that have not been covered sufficiently in previous references. The treatment of pharmacokinetics and bioavailability addresses how phytochemicals get into the body, what happens to them, and how they are metabolized. The book also addresses mechanisms of action, which explains how phytochemicals work at the cellular level, and clinical outcomes and methodology, which focuses on reasonable biomarkers, as well as current and future methods that demonstrate clinical efficacy.

Backed with five decades of compelling evidence, Phytochemicals: Mechanisms of Action is an essential resource for anyone interested in functional foods and nutraceuticals. Throughout the discussions, areas of research need are identified, thus benefiting researchers developing new areas of interest or young researchers just beginning their careers.

Table of Contents

Absorption And Metabolism Of Anthocyanins: Potential Health Effects; Ronald L. Prior

Common Features in the Pathways of
Absorption and Metabolism of Flavonoids; Gary Williamson

Pharmacokinetics and Bioavailability of Green Tea Catechins; Yan Cai and H-H. Sherry Chow

The Importance of In Vivo Metabolism of Polyphenols and Their Biological Action; By Stephen Barnes, Tracy D'Alessandro, Marion C. Kirk, Rakesh P. Patel, Brenda Boersma, and Victor M. Darley-Usmer

Cancer Prevention by Phytochemicals, Modulation of Cell Cycle;
Diane F. Birt, Weiqun Wang, Nancy Pavia,
Angela Au, Chilly Chung, Laura Schmitt and Yu Jiang

Cancer Chemoprevention by Phytopolyphenols Including Flavanoids and Flavonoids through Modulating Signal Transduction Pathways; Jen-Kun Lin

Gene Regulation By Glucosinolate Hydrolysis Products from Broccoli; Kristin E. Stewart, Chu Won Nho, and Elizabeth H. Jeffery

Healthy Food Versus Phytosterol-Fortified Foods for Primary Prevention of Coronary Artery Disease; Douglas S. Lewis, Ph.D and Oksana Matvienko

Vascular Effects Of Resveratrol; Joseph M. Wu, Xiaohua Lu, Junqiao Guo, and Tze-chen Hsieh

Development of a Mixture of Dietary Carotenoids as Cancer Chemopreventive Agents: C57BL/6J Mice as a Useful Animal Model for Efficacy Studies with Carotenoids; Frederick Khachick, Nitin Telang, Fumio Enjo ad Martin Lipkin)

Chemoprevention of Colon Cancer by Curcumin; Bandaru S. Reddy and Chinthalapally V. Rao


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Meskin\, Mark S.; Bidlack\, Wayne R.; Davies\, Audra J.; Lewis\, Douglas S.; Randolph\, R. Keith