Phytochemicals in Health and Disease: 1st Edition (Hardback) book cover

Phytochemicals in Health and Disease

1st Edition

Edited by Yongping Bao, Roger Fenwick

CRC Press

384 pages

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Hardback: 9780824740238
pub: 2004-05-24
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pub: 2004-05-24
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Description

"… well-written and the content is clearly presented. … There are plentiful figures and tables, which are effectively labeled and adequately support the content. …highly recommended for academic and special libraries. …effectively presents current research on phytochemicals in a readable manner."

- E-Streams

"This landmark volume shows how far the field has advanced … . This important volume is filled with reports on what the editors term as the 'new era' in the study of phytochemicals, in which we move from the 'eat more vegetable and fruit' admonition to more detailed information on the biology, molecular biology, regulatory function, and role in human health of phytochemicals. … All workers in phytochemicals should get themselves a copy of this valuable book."

Reviews

"This book, written by multicountry authors, reviews the role of phytochemicals in disease prevention such as eye diseases, cardiovascular diseases and cancer."

-Pediatric Endocrinology Reviews, Vol. 3, No. 1, Sept. 2005

It seems almost a given now that phytochemicals in our diet have health-promoting effects. These phytochemicals, found in fruits, vegetables, teas, and spices have been cited as having the potential to prevent at least three of the leading causes of death in the United States: cancer, cardiovascular disease, and hypertension. Still, many questions remain. Which phytochemicals are the most efficacious? How do they work? Do they act independently or synergistically? How much should we consume and in what form?

Responding to increasing amounts of scientific reports emphasizing the importance of phytochemicals in disease prevention, Phytochemicals in Health and Disease describes the function, metabolism, and biological activities of selected phytochemicals and documents their role in the modulation of enzyme activity, adduct formation, and gene expression.

Contributions from leading researchers describe how phytochemicals obstruct various hormone actions and metabolic pathways such as those associated with the development of cancer and heart disease, examine the benefits of specific food sources, and consider how advances in nutritional genomics are helping to advance our knowledge about these nutrients.

Table of Contents

Nutritional Genomics; Ruan M. Elliott, James R. Bacon, and Yongping Bao

Methods to Study Bioavailability of Phytochemicals; Birgit Holst and Gary Williamson

Characterization of Polyphenol Metabolites; Andrea J. Day, Joseph Rothwell, and Michael R. A. Morgan

Microarray Profiling of Gene Expression Patterns of Genistein in Tumor Cells; Ching Li and Biehuoy Shieh

Gene Regulatory Activity of Ginkgo Biloba L; Gerald Rimbach, Rainer Cermak, and Siegfried Wolffram

Cancer Chemoprevention with Sulforaphane, a Dietary Isothiocyanate; Yuesheng Zhang

Phytochemicals Protect Against Heterocyclic Amine-Induced DNA Adduct Formation; Yongping Bao and Jim Bacon

Organosulfur-Garlic Compounds and Cancer Prevention; John Milner

Polymethylated Flavonoids: Cancer Preventive and Therapeutic Potentials Derived from Anti-inflammatory and Drug Metabolism-Modifying Properties; Akira Murakami and Hajime Ohigashi

Biochemical and Molecular Mechanisms of Cancer Chemoprevention by Tea and Tea Polyphenols; Jen-Kun Lin

The Role of Flavonoids in Protection Against Cataract; Julie Sanderson and W. Russell Mclauchlan

Phytochemicals and the Prevention of Cardiovascular Disease: Potential Roles for Selected Fruits, Herbs, and Spices; Samir Samman

Beneficial Effects of Resveratrol; Ann M. Bode and Zigang Dong

The Role of Lyopene in Human Health; Regina Goralezyk and Ulrich Siler

Future Perspectives in Phytochemical and Health Research; Yongping Bao and Roger Fenwick

Index

About the Series

Oxidative Stress and Disease

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Subject Categories

BISAC Subject Codes/Headings:
MED060000
MEDICAL / Nutrition
SCI013000
SCIENCE / Chemistry / General
TEC012000
TECHNOLOGY & ENGINEERING / Food Science