Several Phyllanthus species are widely used in traditional medicine and herbal formulation for the treatment of a variety of ailments such as flu, dropsy, diabetes, jaundice and bladder calculus. The medicinal properties of these species are due to the presence of lignans, flavonoids, tannins, alkaloids, and terpenoids. Phyllanthin and hypophyllanthin are the major lignans from Phyllanthus species having estrogenic properties that reduces toxicity, vascular tension, and protect hepatocytes. This book deals with the importance of separation techniques in screening of major lignans, flavonoids and terpenoids in Phyllanthus species using HPLC/UPLC coupled with mass spectrometric techniques.
Introduction: Phyllanthus: Ethno- and phytopharmacological review. Screening of phytochemicals in P. amarus by HPLC-ESI-QTOF MS/MS. Quantitative analysis of bioactive compounds in Phyllanthus species and its herbal formulations. DART-TOF-MS analysis P. amarus and study of geographical variations. Conclusion. References.