Phytopharmaceuticals in Cancer Chemoprevention: 1st Edition (Hardback) book cover

Phytopharmaceuticals in Cancer Chemoprevention

1st Edition

Edited by Debasis Bagchi, Harry G. Preuss

CRC Press

688 pages | 12 Color Illus. | 90 B/W Illus.

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Hardback: 9780849315602
pub: 2004-10-28
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pub: 2004-10-28
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During the past decade, a significant amount of research has been conducted on phytopharmaceuticals. Today, a growing body of evidence demonstrates the efficacy of a wide variety of natural products and affirms their potential in the treatment of cancer.

Phytopharmaceuticals in Cancer Chemoprevention focuses on the role of natural supplements in cancer prevention and therapy. The first section covers cancer epidemiology, as well as cancer statistics, current therapies, and potential toxicities involved with existing cancer drugs. The second section begins by discussing the pathophysiology of cancer including mechanistic and molecular aspects of cancer biology, and then explains the etiology of breast cancer, lung cancer, prostate cancer, tobacco and cancer, and gastrointestinal tract cancers, and concludes with the various risk factors related to obesity, exercise and aging. The third section covers phytopharmaceuticals and focuses on cancer health risk factors and the protective abilities of various natural products. The final section features commentary on cancer susceptibility and the value of natural remedies for healthy living.

With contributions from a diverse panel of renowned scientists and cancer biologists, this book covers a broad spectrum of phytopharmaceuticals in relation to their prospective roles in the future of cancer prevention and treatment. It is a valuable resource for nutrition scientists, oncologists, and dietitians in their efforts to conquer the challenge of cancer.

Table of Contents

Section 1. Introduction

Epidemiology of Cancer: An Overview with a Special Emphasis on Cancer Statistics 2003, Henry Rodriquez and Doug Case

Section 2. Pathophysiology of Cancer

Role of DNA Methylation in Cancer and Chemotherapy, Y-Yong Qiu, Bernard L. Mirkin, and Rama S. Dwivedi

Metals, Metalloids and Cancer, Gabriel Keith Harris and Xianglin Shi

Molecular Mechanisms of Asbestos and Silica-induced Lung Cancer, Fei Chen and Val Vallyathan

Free Radicals, Environmental Radiation, and Cancer, Okezie I. Aruoma

Involvement of Receptor Tyrosine Kinases in Lung Cancer: Clinical Importance, Nilanjana Maulik and Gautam Maulik

Smokeless Tobacco, Oxidative Stress, and Cancer, Manashi Bagchi, Sidney J. Stohs, and Debasis Bagchi

The Regulatory Roles of Estrogen in Carcinogenesis: An Overview, Sushanta K. Banerjee, Aminul Islam, and Snigdha Benerjee

NSAIDS and Colorectal Cancer, Henry Lynch, Trudy G. Shaw, Jane F. Lynch, and Hemant K. Roy

Current Perspectives in Gastric Adenocarcinoma, Clinton Snedegar and Bhaskar Banerjee

Adenocarcinoma of the Esophagus, Sandeep Tripathy and Bhaskar Banerjee

Helicobacter pylori and Gastric Cancer , Shinya Toyokuni

Free Radicals, Oxidative Stress and Cancer, Shampa Chatterjee and Aron B. Fisher

Biotransformation and Mechanism of Action of Xenobiotics: What Lessons from the Past Forty Years?, Giovanni Pagano and Marco d'Ischia

Obesity and Cancer, Harry G. Preuss, Manashi Bagchi, Debasis. Bagchi, and G.R. Kaats

Hemangioendothelioma as a Model to Study the Anti-Angiogenic Effects of Dietary Chemopreventive Agents in vivo, Gayle M. Gordillo and Chandan K. Sen

Modulation of Late Adverse Effects of Curative Radiation Therapy for Cancer, John Yarnold and Lone Gothard

Section 3. Phytopharmaceuticals and Chemoprevention

Development of Selected Phytochemicals for Cancer Chemoprevention, Vernon Steele

Phytochemicals as Potential Cancer Chemopreventive Agents, Rajendra G. Mehta and John M. Pezzuto

History of Natural Supplements in Cancer Therapy and Prevention, Gottumukkala V. Subbaraju and Golakoti Trimurtulu

Vitamin C, Vitamin E and b-Carotene in Cancer Chemoprevention, Balz Frei and Jane Higdon

Role of Polyphenols, Flavonoids and Oligomeric Proanthocyanidins in Cancer Chemoprevention, Sidhartha Ray and Debasis Bagchi

Curcumin Derived from Turmeric (Curcuma longa): A Spice for All Seasons, Bharat B. Aggarwal, Anushree Kumar, Manoj S. Aggarwal, and Shishir Shishodia

Tea in Chemoprevention of Cancer, Vaqar Mustafa Adhami, Moammir Hasan Aziz, Nihal Ahmad, and Hasan Mukhtar

Phytoestrogens in Cancer Prevention: Characterization and Beneficial Effects of a New Flavanone, Kurarinone, a Major Phytoestrogen Constituent of Sophora flavescens Ait, A. De Naeyer, W. Venden Berghe, D. De Keukeleire, and Guy Haegeman

Resveratrol in Chemoprevention and Chemotherapy of Breast Cancer, Wisit Tangkeangsirin and Ginette Serrero

Berries and Fruits in Cancer Chemoprevention, Ronald Prior and Jim Joseph

Palm Tocotrienols and Cancer, Kalanithi Nesaretnam

Pycnogenol and Cancer Chemoprevention, F. Virgili, R. Ambra, R. Canali, and O. Gulati

Overview of the Use of Maitake Mushroom and Fraction D in Cancer, Harry G. Preuss, Sensuke Konno, and Debasis Baghci

Taxol in Cancer Treatment and Chemoprevention, Sidney J. Stohs

Lycopene and Cancer, Theresa Visarius, René Gysin, and Angelo Azzi

NADH in Cancer Prevention and Therapy, George D. Birkmayer and Jiren Zhang

Astaxanthin and Cancer Chemoprevention, John E. Dore

Chemopreventive Effects of Selected Spice Ingredients, Young-Joon Surh, Hye-Kyung Na, and Hyong Joo Lee

Coenzyme Q10 and Neoplasia: Overview of Experimental and Clinical Evidence, Emile G. Bliznakov, Raj Chopra, and Hemmi N. Bhagavan

Probiotics in the Prevention of Cancer, Karen Madsen and John Walker

Section 4: Concluding Remarks

Do Dietary Antioxidants Really Help Prevent or Treat Cancer?, Jeffrey Blumberg

Who Gets Cancer? Do Health Foods, Healthy Living, and Natural Antioxidants Really Help?, Jean Carper

About the Series

Modern Nutrition Science

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Subject Categories

BISAC Subject Codes/Headings:
HEALTH & FITNESS / Herbal Medications
MEDICAL / Nutrition
SCIENCE / Chemistry / General