Platelets, Thrombosis and the Vessel Wall aims to highlight the key areas of platelet function in the regulation of haemostasis and thrombosis and covers areas such as platelet production, interaction of platelets with leucocytes, mechanisms of cross-talk between platelets, leukocytes, and endothelium. The two major clinical causes of thrombosis, anti-phospholipid antibodies and genetic predisposition, are also addressed.
1. Thrombopoietin 2. Platelets and Fibrinolysis 3. Von Willebrand Factor and Platelet Adhesion 4. A Unique Receptor for a Unique Function: The Glycoprotein Ib-IX-V Complex in Platelet Adhesion and Activation 5. The Platelet Glycoprotein IIb-IIIa Complex (Integrin aIIbÞ 6. The Platelet Cytoskeleton 7. The Role of Phosphoinositide-derived Second Messenger Molecules in Platelet Activation 8. The Biology of CD36 9. CD9 Structure and Function 10. Neutrophil-Platelet Interaction s 11. P-selectin 12. Role of PECA