680 pages | 173 B/W Illus.
Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.
Water-Soluble Polymers. N-(2-hydroxypropyl) Methacrylamide Copolymer Conjugates. Functional PEG for Drug Delivery. pH-sensitive Polymers for Drug Delivery. Hydrogels. Hydrogels for Oral Administration. Hydrogels for the Controlled Release of Proteins. Thermosensitive Biodegradable Hydrogels for the Delivery of Therapeutic Agents. Stimuli-sensitive Hydrogels. Biodegradable Polymers. Treatment of Malignant Brain Tumors with Controlled-release Local-delivery Polymers. Improving the Stability of PLGA-encapsulated Proteins. Recombinant Polymers for Drug Delivery. Polymeric Nanoparticle Delivery of Therapeutic Cancer Vaccines. Polymer Assemblies. Intelligent Block Copolymer Micelles for the Programmed Delivery of Drugs and Genes. Polymeric Micelles for the Targeting of Hydrophobic Drugs