Practical Aspects of Trapped Ion Mass Spectrometry, Volume V: Applications of Ion Trapping Devices, 1st Edition (Hardback) book cover

Practical Aspects of Trapped Ion Mass Spectrometry, Volume V

Applications of Ion Trapping Devices, 1st Edition

Edited by Raymond E. March, John F.J Todd

CRC Press

566 pages | 237 B/W Illus.

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pub: 2009-11-11
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Description

Widely used in medical research, pharmaceutical and fine chemicals industries, biological and physical sciences, and security and environmental agencies, mass spectrometry techniques are continually under development. In Practical Aspects of Trapped Ion Mass Spectrometry: Volume V, Applications of Ion Trapping Devices, an international panel of authors presents a world-wide view of the practical aspects of recent progress using trapped ion devices.

In contrast to previous texts, which have concentrated generally on a single or limited range of ion trapping techniques, a key feature of this compilation of contributions is its coverage of all the ion trapping techniques currently in use. Spanning sixteen chapters, the text examines:

  • Ion/neutral and ion/ion reactions
  • Structural characterization of proteins and peptides using quadrupole ion trap mass spectrometry, Fourier transform – ion cyclotron resonance (FT-ICR) mass spectrometry, and traveling wave ion mobility mass spectrometry
  • Ion spectroscopy and electron diffraction
  • Conformational analysis of protein isobaric charge states
  • Practical examples of trapped-ion technology that reflect the wide diversity of applications of trapped-ion devices

This text is the first detailed account of the application of new and established mass spectrometric techniques utilizing trapped or confined ions for prolonged investigation and increased sensitivity. Each chapter contains complete references and utilizes a consistent format and writing style, with all terms, acronyms, procedures, and equations thoroughly explained. The strong editorial input to the diverse sections enables readers to readily appreciate the commonalities of topics ranging from theory of instrument operation to proteins, flavonoids, atomic clocks, and single ion mass spectrometry.

Table of Contents

Ion Reactions

Ion/Ion Reactions in Electrodynamic Ion Traps, J. Liu and S. A. McLuckey

Gas-Phase Hydrogen/Deuterium Exchange in Quadrupole Ion Traps, J. E. Chipuk and J. S. Brodbelt

Methods for Multi-Stage Ion Processing Involving Ion/Ion Chemistry in a Quadrupole Linear Ion Trap, G. C. McAlister and J. J. Coon

Ion Conformation and Structure

Chemical Derivatization and Multistage Tandem Mass Spectrometry for Protein Structural Characterization, J. M. Froelich, Y. Lu, and G. E. Reid

Fourier Transform Ion Cyclotron Resonance Mass Spectrometry in the Analysis of Peptides and Proteins, H. J. Cooper

MS/MS Analysis of Peptide-Polyphenols Supramolecular Assemblies: Wine Astringency Approached by ESI-IT-MS, B. Plet and J.-M. Schmitter

Structure and Dynamics of Trapped Ions, J. H. Parks

Applications of Traveling Wave Ion Mobility-Mass Spectrometry, K. Thalassinos and J. H. Scrivens

Ion Spectroscopy

The Spectroscopy of Ions Stored in Trapping Mass Spectrometers, M. W. Forbes, F. O. Talbot, and R. A. Jockusch

Sympathetically-Cooled Single Ion Mass Spectrometry, P. F. Staanum, K. Højbjerre, and M. Drewsen

Ion Trap: A Versatile Tool for the Atomic Clocks of the Future! F. Vedel

Practical Applications

Boundary-Activated Dissociations (BAD) in a Digital Ion Trap (DIT), F. L. Brancia, L. Raveane, A. Berton, and P. Traldi

The Study of Ion/Molecule Reactions at Ambient Pressure with Ion Mobility Spectrometry and Ion Mobility/Mass Spectrometry, G. A. Eiceman and J. A. Stone

The Role of Trapped Ion Mass Spectrometry for Imaging, T. J. Garrett and R. A. Yost

Technology Progress and Application in GC/MS and GC/MS/MS, M. Wang and J. E. George III

Remote Monitoring of Volatile Organic Compounds in Water by Membrane Inlet Mass Spectrometry, R. Pozzi, P. Bocchini, F. Pinelli, and G. C. Galletti

Index

About the Editors

Author

Raymond E. March, PhD, DSc, D(hc), FCIC, is presently Professor Emeritus of Chemistry at Trent University in Peterborough, Ontario, Canada. John F.J. Todd, BSc, PhD, CChem, FRSC, CEng, FInstMC, is currently Emeritus Professor of Mass Spectroscopy at the University of Kent, Canterbury, UK.

Subject Categories

BISAC Subject Codes/Headings:
SCI013000
SCIENCE / Chemistry / General
SCI013010
SCIENCE / Chemistry / Analytic
SCI013060
SCIENCE / Chemistry / Industrial & Technical