Practical Data Analysis for Designed Experiments: 1st Edition (Hardback) book cover

Practical Data Analysis for Designed Experiments

1st Edition

By Brian S. Yandell

Chapman and Hall/CRC

440 pages

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pub: 1997-01-01
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Placing data in the context of the scientific discovery of knowledge through experimentation, Practical Data Analysis for Designed Experiments examines issues of comparing groups and sorting out factor effects and the consequences of imbalance and nesting, then works through more practical applications of the theory. Written in a modern and accessible manner, this book is a useful blend of theory and methods. Exercises included in the text are based on real experiments and real data.


"…the book should be useful for statisticians who are starting out as consultants…also contains much good practical advice based on the writer's experience as a teacher and statistical advisor."

-M. Talbot, Biometrics, December 1998

"…gives a generally lucid and well thought out introduction to the use of data driven approaches for statistical data analysis…the explanations are clear, without being obscured by too much mathematical detail…an excellent basis for a statistics course with an applied orientation, and most institutions that teach statistics or analyse data will probably want a library copy."

-S.N. Wood,Biometrics,December 1998

Table of Contents


Part A: Placing Data in Context

Practical Data Analysis

Effect of Factors

Nature of Data

Summary Tables

Plots for Statistics




Collaboration in Science

Asking Questions

Learning from Plots

Mechanics of a Consulting Session

Philosophy and Ethics

Intelligence, Culture and Learning



Experimental Design

Types of Studies

Designed Experiments

Design Structure

Treatment Structure

Designs in This Book


Part B: Working with Groups of Data

Group Summaries

Graphical Summaries

Estimates of Means and Variance

Assumptions and Pivot Statistics

Interval Estimates of Means

Testing Hypotheses about Means

Formal Inference on the Variance


Comparing Several Means

Linear Contrasts of Means

Overall Test of Difference

Partitioning Sums of Squares

Expected Mean Squares

Power and Sample Size


Multiple Comparisons of Means

Experiment- and Comparison-Wise Error Rates

Comparisons Based on F-Tests

Comparisons Based on Range of Means

Comparisons of Comparisons


Part C: Sorting Out Effects with Data

Factorial Designs

Cell Means Models

Effects Models

Estimable Functions

Linear Constraints

General Form of Estimable Functions


Balanced Experiments

Additive Models

Full Models with Two Factors

Interaction Plots

Higher Orders Models


Model Selection

Pooling Interactions

Selected the "Best" Model

Model Selection Criteria

One Observation per Cell

Tukey's Test for Interaction


Part D: Dealing with Imbalance

Unbalanced Experiments

Unequal Samples

Additive Model

Types I, II, III and IV


Missing Cells

What Are Missing Cells?

Connected Cells and Incomplete Designs

Type IV Comparisons

Latin Square Designs

Fractional Factorial Designs


Linear Models Inference

Matrix Preliminaries

Ordinary Least Squares

Weighted Least Squares

Maximum Likelihood

Restricted Maximum Likelihood

Inference for Fixed Effect Models

Anova and Regression Models


Part E: Questioning Assumptions

Residual Plots

Departures from Assumptions

Incorrect Model

Correlated Responses

Unequal Variance

Non-Normal Data


Comparisons with Unequal Variance

Comparing Means When Variances Are Unequal

Weighted Analysis of Variances

Satterthwaite Approximation

Generalized Inference

Testing for Unequal Variances


Getting Free from Assumptions

Transforming Data

Comparisons Using Ranks


Monte Carlo Methods


Part F: Regressing with Factors

Ordered Groups

Groups in a Line

Testing for Linearity

Path Analysis Diagrams

Regression Calibration

Classical Error in Variables


Parallel Lines

Parallel Lines Model

Adjusted Estimates

Plots with Symbols

Sequential Tests with Multiple Responses

Sequential Tests with Driving Covariate

Adjusted (Type III) Tests of Hypotheses

Different Slopes for Different Groups


Multiple Responses

Overall Tests for Group Differences

Matrix Analog to F Test

How Do Groups Differ?

Causal Models

Part G: Deciding on Fixed or Random Effects

Models with Random Effects

Single Factor Random Model

Test for Class Variation

Distribution of Sums of Squares

Variance Components

Grand Menu


General Random Models

Two Factor Random Models

Unbalanced Two-Factor Random Model

General Random Model

Quadratic Forms in Random Effects

Application to Two Factor Random Model


Mixed Effect Models

Two Factor Mixed Models

General Mixed Models


Part H: Nesting Experimental Units

Nested Designs



Nested and Crossed Factors

Nesting of Fixed Effects

Nesting of Random Effects


Split Plot Design

Several Views of Split Plot

Split Plot Model

Contrasts in a Split Plot


General Nested Designs

Extensions of Split Plot

Split Plot

Imbalance in Nested Designs

Covariates in Nested Designs

Explained Variation in Nested Designs


Part I: Repeating Measures on Subjects

Repeated Measures as Split Plot

Repeated Measures Designs

Repeated Measures Model

Split Plot More or Less

Expected Mean Squares under Sphericity

Contrasts under Sphericity


Adjustments for Correlation

Adjustments to Split Plot

Contrasts over Time

Multivariate Repeated Measures


Cross-Over Design

Cross-Over Model

Confounding in Cross-Over Designs

Partition of Sum of Squares

Replicated Latin Square Design

General Cross-Over Designs




About the Series

Chapman & Hall/CRC Texts in Statistical Science

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Subject Categories

BISAC Subject Codes/Headings:
MATHEMATICS / Probability & Statistics / General