The latest volume in the Practical Phlebology series, Deep Vein Thrombosis provides trainee and practicing physicians with the ideal illustrative guide to the etiology, diagnosis, and management of deep vein thrombosis (DVT). Based on peer-reviewed literature and quality clinical trials, the book is also an essential resource for academicians.
Topics include:
- Epidemiology, natural history, and etiology of DVT
- DVT prophylaxis
- Diagnostic techniques
- Anticoagulation, thrombus removal, catheter-based interventions, and thrombolysis
- Inferior vena cava filters
- Heparin-induced thrombocytopenia
- Femoral endovenectomy and endoluminal recanalization
Natural history of acute DVT
DVT and mortality
Thrombus resolution
DVT, valve function, and recurrence
Not all DVTs are the same
Etiology
Etiology
Vein wall injury
DVT prophylaxis
Risk stratification
Prophylaxis guidelines
References
Diagnosis of acute DVT
Clinical evaluation
Ascending phlebography
Venous duplex ultrasound
Computerized tomographic venography
Magnetic resonance venography
D-dimer tests
Anticoagulants
Unfractionated heparin
Low-molecular-weight heparins
Fondaparinux
Direct thrombin inhibitors
Warfarin compounds (Vitamin K antagonists)
Danaparoid
References
New oral anticoagulants
Clinical trial development
VTE prophylaxis in orthopedic patients
VTE prophylaxis in medically ill patients
Treatment of acute VTE
Reversal of the anticoagulant effect of NOACs
Management of acute DVT: Anticoagulation
Initial anticoagulation
Duration of anticoagulation
Recurrent DVT
DVT and malignancy
Tailoring duration of anticoagulation
Ambulation and compression
Strategy of thrombus removal
Background
Rationale for thrombus removal
Treatment options for thrombus removal
Recurrent DVT
Inferior vena cava filters
Indications
Filter types
Clinical decision making
Randomized trials
Hemodynamic performance
Decision matrix
Heparin-induced thrombocytopenia
Overview
Clinical presentation
Diagnosis
Management
Common femoral endovenectomy and endoluminal recanalization for chronic postthrombotic iliofemoral venous obstruction
Overview
Operative procedure
Operative complications
Clinical outcomes
Perspective
Biography
Anthony J. Comerot, MD, FACS, FACC, is the director of the Jobst Vascular Institute at Toledo Hospital in Ohio and adjunct professor of surgery at the University of Michigan. He received his medical degree from Temple University School of Medicine in Philadelphia, Pennsylvania, and completed his general surgery residency at Temple University Hospital and his vascular surgery fellowship at Good Samaritan Hospital, Cincinnati, Ohio.
Dr. Comerota has been a major contributor to the development of some of the newest forms of treatment for vascular disease and has been the principal investigator of seven major national trials and a co-investigator of numerous others. His research interests span a broad range of arterial and venous disorders, including the management of acute DVT, therapeutic angiogenesis, noninvasive diagnosis of vascular disease, development of new devices, new drug development, and the effects of platelet-inhibiting drugs. He has received over $5 million in research funding, including support from the National Institutes of Health (NIH), the American Heart Association, and the American Diabetes Association.
"This is an invaluable book for clinicians wishing to increase their knowledge about DVT and how to care for patients with this disease process. … well written with complete yet understandable explanations of the disease process and how to treat patients with each type of DVT." (4 stars)
—Courtney M Daly, MD (Northwestern University Feinberg School of Medicine) in Doody’s Review Service