1st Edition

Practical Phlebology
Deep Vein Thrombosis

ISBN 9781444146097
Published November 18, 2013 by CRC Press
149 Pages

USD $200.00

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Book Description

The latest volume in the Practical Phlebology series, Deep Vein Thrombosis provides trainee and practicing physicians with the ideal illustrative guide to the etiology, diagnosis, and management of deep vein thrombosis (DVT). Based on peer-reviewed literature and quality clinical trials, the book is also an essential resource for academicians.

Topics include:

  • Epidemiology, natural history, and etiology of DVT
  • DVT prophylaxis
  • Diagnostic techniques
  • Anticoagulation, thrombus removal, catheter-based interventions, and thrombolysis
  • Inferior vena cava filters
  • Heparin-induced thrombocytopenia
  • Femoral endovenectomy and endoluminal recanalization

Table of Contents

Natural history of acute DVT

DVT and mortality

Thrombus resolution

DVT, valve function, and recurrence

Not all DVTs are the same



Vein wall injury

DVT prophylaxis

Risk stratification

Prophylaxis guidelines


Diagnosis of acute DVT

Clinical evaluation

Ascending phlebography

Venous duplex ultrasound

Computerized tomographic venography

Magnetic resonance venography

D-dimer tests


Unfractionated heparin

Low-molecular-weight heparins


Direct thrombin inhibitors

Warfarin compounds (Vitamin K antagonists)



New oral anticoagulants

Clinical trial development

VTE prophylaxis in orthopedic patients

VTE prophylaxis in medically ill patients

Treatment of acute VTE

Reversal of the anticoagulant effect of NOACs

Management of acute DVT: Anticoagulation

Initial anticoagulation

Duration of anticoagulation

Recurrent DVT

DVT and malignancy

Tailoring duration of anticoagulation

Ambulation and compression

Strategy of thrombus removal


Rationale for thrombus removal

Treatment options for thrombus removal

Recurrent DVT

Inferior vena cava filters


Filter types

Clinical decision making

Randomized trials

Hemodynamic performance

Decision matrix

Heparin-induced thrombocytopenia


Clinical presentation



Common femoral endovenectomy and endoluminal recanalization for chronic postthrombotic iliofemoral venous obstruction


Operative procedure

Operative complications

Clinical outcomes


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Anthony J. Comerot, MD, FACS, FACC, is the director of the Jobst Vascular Institute at Toledo Hospital in Ohio and adjunct professor of surgery at the University of Michigan. He received his medical degree from Temple University School of Medicine in Philadelphia, Pennsylvania, and completed his general surgery residency at Temple University Hospital and his vascular surgery fellowship at Good Samaritan Hospital, Cincinnati, Ohio.

Dr. Comerota has been a major contributor to the development of some of the newest forms of treatment for vascular disease and has been the principal investigator of seven major national trials and a co-investigator of numerous others. His research interests span a broad range of arterial and venous disorders, including the management of acute DVT, therapeutic angiogenesis, noninvasive diagnosis of vascular disease, development of new devices, new drug development, and the effects of platelet-inhibiting drugs. He has received over $5 million in research funding, including support from the National Institutes of Health (NIH), the American Heart Association, and the American Diabetes Association.



"This is an invaluable book for clinicians wishing to increase their knowledge about DVT and how to care for patients with this disease process. … well written with complete yet understandable explanations of the disease process and how to treat patients with each type of DVT." (4 stars)
—Courtney M Daly, MD (Northwestern University Feinberg School of Medicine) in Doody’s Review Service