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At the cutting-edge of maternal and neonatal management and research, this reference presents the most recent advances in fetal DNA/RNA, embryoscopy/fetoscopy, open fetal surgery, and ethnic population screening to manage pre-existing and newly detected maternal medical complications, detect genetic and congenital abnormalities, prevent preterm births, and optimize pregnancy outcomes. With illustrative color photographs, this source offers contributions by esteemed professionals at respected institutions around the globe and covers legal issues concerning prenatal assessment and diagnosis.
Table of Contents
PRENATAL SCREENING. First Trimester Serum Screening. Maternal Serum Screening for Down Syndrome. Nuchal Translucency Screening. Nasal Bone in Screening for Trisomy 21. Screening for Neural Tube Defects: Ultrasound and Serum Markers. Antenatal Screening for Down's Syndrome Using the Integrated Test. Genetic Ultrasound Scan -Second Trimester
Fetal Cells in Maternal Blood:Diagnostic and Therapeutic Implications. Fetal DNA and mRNA in Maternal Plasma. Ethnic Population Screening. Pathophysiology of Increased Nuchal Translucency. PRENATAL DIAGNOSIS. Invasive Prenatal Diagnostic Techniques. Prenatal Diagnosis of Multifetal Pregnancies. Embryoscopy in the First Trimester of Pregnancy. Prenatal Diagnosis of Chromosome Abnormalities. Prenatal DNA Testing. Preimplantation Genetic Diagnosis. Fetal Anomaly Scan. The Role of 3-Dimensional Ultrasound in Prenatal Diagnosis. Fetal Magnetic Resonance Imaging. PRENATAL THERAPY. Prevention of Labor. Pharmacological Therapy. Intrauterine Intravascular Treatment. Gastroschisis. Twin to Twin Transfusion. Fetoscopic Instrumentation and Techniques. Open Fetal Surgery. Termination of Pregnancy. Fetal Reduction. Gene Therapy. ETHICS AND LEGISLATION. Maternal/Fetal Conflict: A Legal and Ethical Conundrum. Ethical Issues
John M. G. van Vugt, Lee P. Shulman